Replace margarine with natural fats
Margarine begins as liquid vegetable oils (soybean, canola) that are already processed with high heat and pressure, creating oxidized oils. To solidify them, they undergo hydrogenation, which produces trans fats — unnatural, man-made molecules that Ekberg calls 'closer to plastic than food.' These fats become incorporated into cell membranes, making them rigid and disrupting neural signal processing. They also promote systemic inflammation, interfere with omega-3 metabolism, and impair mitochondrial conversion of fuel into ATP. Historically, natural saturated fats like coconut oil and beef tallow were used for movie popcorn and French fries; they were stable and safe but were replaced with these inflammatory oils plus artificial flavors, a switch that Ekberg says caused more disease through engineering rather than better health.
Trans fats incorporate into the phospholipid bilayer of cell membranes, increasing membrane rigidity. This distorts membrane protein function, including receptors and ion channels, leading to impaired neurotransmission. Additionally, trans fats promote the production of pro-inflammatory cytokines and disrupt the desaturase enzymes needed to convert omega-3s into anti-inflammatory eicosanoids. In mitochondria, they alter cardiolipin composition, reducing the efficiency of the electron transport chain and ATP synthesis, which increases oxidative stress.
Instead of these margarins and these fake fats, what you want to use are real fats, natural fats like butter and ghee and tallow and extra virgin olive oil.

