Bromelain 750 mg daily general protocol
Hubert Czerniak dedicates a large portion of the episode to bromelain, starting with its source (stem > fruit). He explains that bromelain is a mixture of proteolytic enzymes with optimal pH 6‑7. Unlike many enzymes, it binds to plasma proteins, preserving its activity and allowing tissue delivery. Its maximum plasma concentration occurs one hour after oral intake. He lists a comprehensive range of actions: analgesic, anti‑inflammatory via cyclo‑oxygenase‑2 inhibition, anti‑aggregatory, anti‑edematous, tumour‑growth inhibition, aid in inflammatory bowel disease, weight loss support, immune enhancement (T‑cell activity), allergy and sinusitis relief, reduction of delayed‑onset muscle soreness, post‑surgical pain, and even lichen planus. A key Alzheimer’s angle is the breakdown of beta‑amyloid by a trypsin‑bromelain complex. He then states the recommended daily dose: 750 mg. For context, he notes that doses of 540‑1890 mg/day were used in joint inflammation studies. High safety margins are given: mice LD50 >10 g/kg, dogs tolerated 750 mg/kg for 6 months, rats 1500 mg/kg with no toxicity. He also mentions that bromelain improves absorption of curcumin, glutathione, penicillin and tetracyclines. The extended mechanism: bromelain cleaves damaged proteins, creating space for new tissue formation, which underlies its anti‑inflammatory and wound‑healing effects.
Bromelain enzymes hydrolyse peptide bonds; by binding α2‑macroglobulin and other plasma proteins, they evade rapid degradation and reach inflamed tissues. There they suppress COX‑2, reduce prostaglandin synthesis, degrade fibrin (fibrinolytic), inhibit platelet aggregation, and break down cell‑surface receptors involved in tumour metastasis. Antioxidant action scavenges free radicals. Proteolysis of damaged extracellular matrix proteins clears debris and stimulates regeneration.
zaleca się dobową dawkę 750 mg bromelainy

