72-Hour Prolonged Fast (Monthly)
Berg frames the monthly 72‑hour fast as a non‑negotiable health reset. He explains that the subjective benefits include euphoria and mental clarity, while the cellular benefits — autophagy, insulin control, inflammation reduction — stack up to what he believes is a cancer‑preventing protocol. Anecdotally, he shares the story of a depressed, suicidal man who locked himself in a room to starve but by day three felt incredible and discovered the science of fasting, which turned his life around. Berg also points to a case of type‑1 diabetics running marathons while fasting for five days without soreness, showing potent anti‑inflammatory protection. He warns against trying this without prior intermittent fasting adaptation and insists that the most important practical element is sea salt, as many give up because of electrolyte imbalance. To reinforce the monthly cadence, he argues that doing this regularly conditions not just the body but the will, making each subsequent fast easier and more effective. The protocol is not just a diet break but a holistic physical‑mental discipline that, he says, should be combined with long walks for added oxygen.
After 48–72 hours without food, glycogen stores are depleted and the body enters deep ketosis. Autophagy ramps up to clear damaged proteins and organelles. Inflammation markers drop because fasting inhibits pro‑inflammatory pathways and lowers insulin. Growth hormone spikes to protect lean mass and mobilise fat. Endogenous ketone bodies signal longevity genes (sirtuins, FOXO) and cannot be utilised by many cancer cells, unlike dietary or supplemental ketones. The simultaneous insulin suppression removes a key growth signal for tumours and puts the body into a catabolic, repair‑focused mode.
This is why I recommend doing a 72-hour fast every single month.

