Minimum Total Protein Intake to Equalize Muscle Gain from Plant and Animal Protein
Norton builds this recommendation from the study's findings and his broader knowledge. He explains that when total protein is below ~1.6 g/kg, lower-quality plant proteins might underperform because the essential amino acid (especially leucine) dose is insufficient to fully stimulate muscle protein synthesis. However, once protein intake surpasses about 1.6 g/kg, even plant proteins provide enough leucine to max out the anabolic response, effectively 'capping out the anabolic system.' He concedes that in a perfect, very long-term RCT with resistance-trained people eating exactly 1.6 g/kg from predominantly plant vs. animal sources, there might be a tiny, almost undetectable difference, but in practice total protein intake is the overwhelming determinant. He also advises not to chronically under-fuel or diet on very low calories, as that hampers muscle building regardless of protein source. The message: prioritize hitting a high protein target, and the plant-animal debate largely vanishes.
Muscle protein synthesis is triggered by the essential amino acid leucine and the overall EAA profile. At protein intakes above 1.6 g/kg, the amount of leucine and other EAAs provided by even moderate-digestibility plant proteins is sufficient to repeatedly maximally stimulate mTORC1 signaling, so anabolic ceilings are reached irrespective of the source. Below that, plant proteins might deliver suboptimal leucine pulses, limiting the anabolic response.
if you get in enough total protein, and I'm talking about above like 1.6 g per kilogram of body weight, the differences between plant and animal for building muscle, basically there is no difference because you get to a high enough level of protein that you're capping out the anabolic system.

