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Episode
Monk Fasting is the Most Powerful Method to Drop Fat, Add Brain Cells and Reset Sleep
~70 min
Episode Brief·YouTube

Monk Fasting is the Most Powerful Method to Drop Fat, Add Brain Cells and Reset Sleep

Thomas DeLauer
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TL;DR

The four things you'd lose by not watching

4 items

TL;DR

The four things you'd lose by not watching

4 items
1

A 36-hour 'monk fast' once a week triggers a cascade of metabolic, hormonal, and cognitive benefits: deep fat burning, autophagy (cellular cleanup), a 5x growth hormone surge for fat mobilization and muscle preservation, and a BDNF-driven brain boost and sleep reset.

2

The final 28–36 hour window is non-negotiable—this is when ketone production doubles, autophagy peaks, and fat-to-glucose conversion maximizes, mirroring the focus and clarity monastic traditions sought.

3

Breaking the fast correctly is as critical as the fast itself: start with bone broth to soothe the gut, then lean protein 60 minutes later to capitalize on sky-high insulin sensitivity without the insulating effect of dietary fat, followed by a balanced whole-foods meal 2 hours later.

4

The speaker recommends ButcherBox grass-fed meats as his go-to protein source for the lean refeed and provides a step-by-step weekly protocol that includes hydration, electrolytes, and light exercise.

Protocols

Concrete recipes — what, when, how much, and why

5 items

Weekly 36-hour monk fast

WhatComplete a 36-hour fast starting after dinner (e.g., Sunday 6pm) and ending the following morning 36 hours later (e.g., Tuesday 6am). During the fast, consume only water, black coffee, tea, and optionally a pinch of salt or electrolyte supplements. Zero calories. After the fast, follow a graduated refeeding protocol.
WhenOnce per week, once every two weeks, or once per month, depending on fat loss goals and adaptation. The speaker suggests Sunday evening to Tuesday morning as a template.
Dose36 hours total; 0 calories consumed.
For whomAdults seeking fat loss, improved metabolic health, cellular rejuvenation, and cognitive clarity. Not for pregnant or nursing women, those with eating disorders, or individuals with medical conditions without physician clearance.
WhyTriggers deep metabolic switching (glycogen depletion → gluconeogenesis → ketosis), maximizes autophagy after 28 hours, causes a 5x growth hormone surge for lipolysis and muscle preservation, resets insulin sensitivity, and elevates BDNF for brain benefits and sleep reset.
CaveatsMay experience hunger during the first day, slightly elevated adrenaline and possible poor sleep on the second night. Lightheadedness or fatigue can occur if electrolytes are not maintained. Not recommended for those with high physical demands without adaptation. The speaker advises against intense exercise during the fast.

The speaker presents the fast as a deliberate, rhythmic reset rather than a daily lifestyle. He breaks down the physiological timeline into digestible stages, emphasizing that the final push from 28 to 36 hours is where the deepest benefits accumulate—autophagy peaks, fat-to-glucose conversion becomes efficient, and the hormonal environment is optimized for fat loss and tissue repair. The protocol's simplicity (just don't eat for 36 hours) is undergirded by the specific timing of when to start (after an evening meal) to maximize the overlapping windows of sleep and the natural fasting day. He recommends maintaining hydration and using black coffee or tea to manage hunger, while noting that the hunger itself is a signal of metabolic adaptation, not muscle wasting. The psychological component is also addressed: the fast forces discipline but is infrequent enough to be sustainable, and the refeeding strategy ensures the benefits are locked in.

Mechanism

The fast depletes liver and muscle glycogen within 12–16 hours, forcing a shift to gluconeogenesis (using fat and some amino acids to produce glucose) at 16–24 hours. Between 20–28 hours, hepatic ketone production ramps up, with beta-hydroxybutyrate doubling, providing cleaner fuel and reducing oxidative stress. At 28–36 hours, sustained energy demand keeps fat oxidation high while AMPK activation triggers autophagy (cellular clean-up) and growth hormone secretion, which is lipolytic and muscle-sparing. Prolonged insulin absence dramatically upregulates insulin receptor sensitivity, and the metabolic stress stimulates BDNF expression in the brain, promoting neurogenesis and synaptic plasticity.

Personal experience

The speaker describes this as his protocol, implying personal use and extensive research. He specifically mentions using ButcherBox meats for the refeed and having tried various methods to arrive at this optimal schedule.

Start your 36-hour fast after your last meal on like a Sunday evening... that's going to be your calorie cut off. This sets you up to fast through Monday and you break your fast Tuesday morning. So, the actual fasting day... you're going to hydrate, and I recommend even distracting yourself... zero calories.

Also said
“Your primary tools are going to be water. You can have black coffee, maybe some tea... maybe even a pinch of salt or some electrolyte supplements or something. That will help you manage the hunger and it can help you keep your energy a little bit higher.”— Gives specifics on what is permitted during the fast and how to mitigate discomfort.
“Use that hunger sort of as a signal that your body's adapting rather than breaking down... it's tapping into the fat stores and it takes a second for enzyatic function and flexibility to kick in.”— Reframes hunger psychologically, a key support for adherence.

Reintroduce food with bone broth

WhatBreak the 36-hour fast by first consuming bone broth. Wait 60 minutes before eating solid food.
WhenImmediately after the 36-hour fast completes (e.g., Tuesday morning upon waking).
DoseOne serving of bone broth; no fixed volume defined, but a cup is implied. Wait 60 minutes before the next food.
For whomAnyone breaking a 36-hour fast, especially those with sensitive digestion or who want to optimize gut health.
WhyBone broth is gentle on the rested digestive system, provides collagen, amino acids (glycine), and helps repair the gut lining while priming it for more substantial nutrients without causing a large insulin spike or digestive shock.
CaveatsIf using commercially prepared bone broth, check for additives. Homemade bone broth is preferable.

The speaker underscores the importance of a phased refeed, comparing it to introducing nutrients to a freshly cleaned engine. He warns against diving into a large meal immediately, which could shock the digestive system and cause a massive insulin spike. Instead, bone broth acts as a signaling molecule to the gut, providing hydration and building blocks for the intestinal lining. This step is particularly important because the 36-hour fast upregulates autophagy and stem cell activity in the gut, and the right first inputs can maximize the regenerative effect.

Mechanism

After a prolonged fast, the gastrointestinal tract is in a resting state with reduced permeability. Bone broth provides easily assimilated nutrients—glycine, proline, and gelatin—that support mucosal repair and stimulate gastric secretions, easing the transition back to solid foods. It does not provoke a significant insulin response, allowing the heightened insulin sensitivity to persist until the upcoming protein meal.

Personal experience

The speaker recommends this from his own practice, noting that bone broth is his go-to for breaking longer fasts.

Reintroduction with bone broth... start with something super gentle. Bone broth is perfect because you get the collagen, you get the aminos, you get the glycine, and this is really good for the gut lining, and it preps you for food.

Lean protein 60 minutes after bone broth

WhatConsume a serving of lean protein (e.g., grilled chicken breast, fish, or 93–96% lean beef) about 60 minutes after finishing the bone broth.
When60 minutes after the bone broth, on the same morning the fast is broken.
DoseOne serving ( roughly 4–6 ounces of lean meat) is implied; no exact grams given.
For whomIndividuals wanting to rebuild muscle and restore nutrients after a fast without gaining fat.
WhyAt this point, insulin sensitivity is extremely high. A lean protein source provides amino acids and causes an insulin spike, which efficiently shuttles amino acids into muscle cells for repair and glycogen replenishment. Keeping the protein lean (low in fat) ensures the insulin spike is not blunted, maximizing anabolic uptake.
CaveatsAvoid fatty cuts of meat or adding oils/butter. If vegetarian, a lean plant protein with a similar insulinogenic profile (like pea protein isolate) could be considered, though the speaker emphasizes animal sources.

The speaker explains that this step is a deliberate exploitation of the fasted state's metabolic window. Many people fear insulin spikes, but in this context, it's a tool. By pairing the insulin sensitivity from fasting with a lean protein source, you are effectively mimicking a post-workout anabolic window without the need for carbohydrates. He even specifies 93-96% lean beef to ensure minimal fat content. He suggests that this timing (60 minutes post-broth) allows the gut to have received its gentle wake-up call before handling denser protein, preventing digestive distress while still capturing the sensitivity window before it begins to wane hours later.

Mechanism

Dietary protein, especially from complete animal sources, stimulates a robust insulin release via incretin hormones and direct amino acid sensing. With post-fast hyper-sensitivity, this insulin surge promotes GLUT4 translocation in muscle and activates mTORC1, driving protein synthesis and glycogen synthesis. The absence of dietary fat prevents intramyocellular lipid accumulation that could otherwise impair insulin signaling, thus directing the anabolic response precisely to muscle tissue.

Personal experience

The speaker uses ButcherBox grass-fed meats for this step and personally selects lean cuts like bison or lean beef.

I want you to go with lean protein about 60 minutes after the bone broth... grilled chicken, fish, or maybe like 93 to 96% lean beef. Okay? Something super lean. And why is it lean? Because you're so insulin sensitive at this point. Protein is going to be more efficiently shuttled in your muscle cells. So, I'd rather you have it without the fat that can slow that insulin spike.

Also said
“Yes, protein spikes insulin. So, I want you to be able to get that insulin spike without the fat.”— Explicitly states the counterintuitive strategy of intentionally spiking insulin.

Balanced whole-foods meal 2 hours post-protein

WhatAbout 2 hours after the lean protein, consume a larger balanced meal consisting of whole, unprocessed foods including vegetables, healthy fats, and carbohydrates if desired.
When2 hours after the lean protein meal, still on the same break-fast day (morning to early afternoon).
DoseOne full meal; no specific calorie target, but guidance is to focus on whole foods.
For whomAnyone completing the refeed; designed for all healthy adults.
WhyBy this point, the digestive system has been gradually reawakened. A balanced meal restores fiber, micronutrients, and energy while the body remains insulin-sensitive but no longer in the acute post-fast window. This locks in the metabolic benefits and ensures sustained energy.
CaveatsAvoid ultra-processed foods that could provoke inflammation or excessive insulin spikes now that the earlier sensitivity window has passed. Keep it whole and unprocessed.

The speaker frames this final step as restoring nutritional completeness. After the fast and the targeted refeed, the body is primed to absorb micronutrients and replenish glycogen stores fully. He advises a focus on whole, unprocessed foods—this is not about restriction but about quality. This gradual, three-stage refeed ensures the transition back to regular eating is smooth and that the cellular adaptations from the fast are preserved rather than erased by a sudden heavy meal.

After you have that lean protein, about 2 hours after that, have a larger balanced meal. This is where you're going to focus just plat out on whole unprocessed foods.

Light exercise during the fast

WhatPerform light exercise like walking, gentle cardio, or light resistance training on the fasting day to maintain muscle and distract from hunger, but avoid intense or prolonged exertion.
WhenDuring the 36-hour fast, particularly on the full fasting day (e.g., Monday).
DoseNo specific duration; implied to be short sessions that don't cause excessive fatigue.
For whomThose who feel up to it; not mandatory but helpful for most.
WhyLight activity helps preserve muscle mass, improves the psychological experience of the fast, and promotes metabolic flexibility without adding excessive stress that could compromise the body's ability to focus on cellular repair.
CaveatsDo not push intensely; the body is already in a stressed state, and overexertion could hinder autophagy and recovery. Listen to your body and keep intensity low.

The speaker suggests using light exercise as a tool to distract from hunger and to keep the body in a fat-burning mode without tipping into excessive cortisol production. He contrasts it with the energy demands of digestion—by not eating, the energy normally used for digestion can be redirected to repair processes, and adding light movement supports circulation and gentle stress adaptation while preserving muscle tone.

Mechanism

Low-intensity exercise during fasting increases fatty acid oxidation and AMPK activation, synergizing with the fast's signals for autophagy and fat utilization. It also helps maintain neuromuscular activation and muscle fiber integrity without depleting energy reserves needed for repair processes.

Maybe some light exercise, maybe go for a walk, maybe go for a run, do some resistance training can help maintain the muscle that's on you. Just don't push it super super hard because you're already in a stressed state. You want to preserve enough energy for your body to actually focus on cellular repair.

What's new

Personal practice updates, fresh positions, predictions

4 items

The 36-hour monk fast as a weekly metabolic ignition point

The speaker reframes extended fasting not as a daily habit but as a once-weekly 36-hour protocol that condenses fat burning, autophagy, hormone optimization, and neurogenesis into a single block.

Why this matters: It challenges the daily intermittent fasting trend by arguing that the 28–36 hour window delivers a disproportionate share of benefits, combining metabolic flexibility with a practical, non-obsessive schedule.

Background

Mainstream fasting advice often centers on 16:8 or occasional 24-hour fasts. The idea that a longer, infrequent fast can serve as a holistic reset—without daily deprivation—is a departure from that norm.

The speaker walks through the body's fuel transitions hour by hour. From 12–16 hours, glycogen stores deplete. At 16–24 hours, gluconeogenesis converts fat (and some amino acids) into glucose for the brain, demonstrating metabolic flexibility. Ketone production becomes prominent between 20–28 hours, with a study showing ketone levels doubling in that window, providing a cleaner-burning fuel with antioxidant properties. However, the 28–36 hour peak is where the 'monk fast' earns its name: sustained fat-to-glucose conversion forces the body to master fat utilization, while autophagy, hormone surges, and BDNF production all reach maximal intensity. The speaker argues that these later hours are what ancient monastic traditions recognized as a state of heightened clarity and spiritual connection, and that modern metabolisms have lost this metabolic flexibility but can regain it through the 36-hour fast.

It's called a monk fast because that 28 to 36-hour peak is when you get the real benefits. And they actually feel they get closer to like enlightenment, right? they feel like they can actually be spiritually clicked in better because you get this heightened brain function.

Also said
“There was a review published in the annual review of nutrition and it highlighted this. They called it sort of a metabolic flexibility piece showing how your body really becomes powerful at sourcing its own glucose when dietary carbs aren't available.”— Explains why the body doesn't rely solely on muscle breakdown but uses fat to make glucose, countering a common fear about fasting catabolism.
“There was a study that really showed that between 20 and 28 hours ketone levels literally double.”— Quantifies the ketone surge that occurs in the specific window leading up to the monk fast peak.

Realistic growth hormone surge during a 36-hour fast

The speaker debunks the often-cited 2,000% growth hormone increase and instead highlights a 5-fold elevation that primarily acts as a fat mobilizer and muscle sparing agent, not a bodybuilding hypertrophic stimulus.

Why this matters: Provides a sober, mechanistic interpretation of growth hormone data that corrects exaggerated claims and repositions GH as a lipolytic tool for fat loss, not magic muscle growth.

Background

Many online sources claim fasting causes a 2,000% spike in growth hormone, leading to misconceptions that one can build significant muscle without food. The speaker counters this by referencing the Journal of Clinical Investigation and emphasizing pulsatile secretion.

The speaker explains that while GH levels can increase fivefold during extended fasting, it's crucial to understand that the pulsatile nature of GH means total 24-hour output is far less dramatic than a single measurement suggests. More importantly, growth hormone in this context is primarily lipolytic—it signals adipocytes to release stored triglycerides and convert them to free fatty acids for energy. At the same time, it helps spare lean tissue from being catabolized, creating a hormonal environment that shunts the body toward fat oxidation while protecting muscle. The net effect is fat loss without the loss of strength or muscle mass, which is the optimal scenario for body recomposition during fasting.

Some studies published... in the journal of clinical investigation, and that showed that GH levels can increase by fivefold during extended fasting. That's a little bit more realistic than say a 2,000% increase, cuz that's again pulsatile. It's not really valid.

Also said
“This elevated growth hormone is really important more so as a fat mobilizer. Growth hormone is very lipolytic. It signals your fat cells to release the stored triglycerides and it helps convert them into free fatty acids for energy.”— Clarifies the primary metabolic role of GH during a fast, shifting the narrative from anabolic to catabolic-lipolytic.

Post-fast refeeding with lean protein to exploit insulin sensitivity

After a 36-hour fast, not only is cellular insulin sensitivity heightened, but the first substantial refeed should be lean protein alone (without dietary fat) so that the insulin spike efficiently shuttles amino acids into muscle instead of being blunted by fat.

Why this matters: This refeeding strategy inverts the common practice of breaking a fast with a high-fat meal or a full composition plate. The speaker intentionally uses the insulinogenic property of protein to maximize anabolic uptake precisely because the body is uniquely primed to handle insulin after the fast.

Background

Standard refeeding advice often suggests a small, mixed meal or a high-fat option to avoid insulin spikes. The speaker argues that after a prolonged fast, the body's extreme insulin sensitivity makes an insulin spike desirable for nutrient partitioning.

The 36-hour fast resets insulin sensitivity to a degree that even a protein-induced insulin release becomes a targeted anabolic tool. The pancreas has been at rest, and cellular insulin receptors are freshly responsive. Introducing lean protein—chicken breast, fish, or 93-96% lean beef—60 minutes after a gentle bone broth primer provides amino acids for muscle repair without dietary fat slowing the insulin response. This approach directs the protein toward muscle synthesis and glycogen replenishment rather than allowing it to be stored as fat. The speaker explicitly advises against fat at this stage, not because fat is unhealthy, but because it would dampen the insulin spike and reduce the efficiency of nutrient shuttling, undermining the metabolic window created by the fast.

Personal experience

The speaker personally uses ButcherBox meats for this step and recommends lean cuts. He notes he has used this protocol for fat loss and muscle maintenance.

Because you're so insulin sensitive at this point. Protein is going to be more efficiently shuttled in your muscle cells. So, I'd rather you have it without the fat that can slow that insulin spike.

Also said
“Then I want you to go with lean protein about 60 minutes after the bone broth... grilled chicken, fish, or maybe like 93 to 96% lean beef.”— Specific food choices and timing for the lean protein refeed.
“Yes, protein spikes insulin. So, I want you to be able to get that insulin spike without the fat.”— Acknowledges the deliberate use of an insulin spike after a fast.

Sleep disruption during extended fasting is normal

The speaker notes that it's common to not sleep well on the second night of a 36-hour fast due to elevated adrenaline, and this should be expected rather than feared.

Why this matters: Validates a frequent side effect and normalizes it as a physiological response to the fast, not a sign of harm.

Background

Many people abandon extended fasts because they experience poor sleep, assuming it's a sign of stress or metabolic distress. The speaker reframes it as an expected catecholamine-driven state.

You'll go to bed Monday and you'll probably be a little hungry, okay? Or maybe you might not even sleep real good Monday night. That's kind of normal because your adrenaline's elevated.

Recommendations

Products, supplements, and tools mentioned in the episode

2 items

Electrolyte supplements (salt, potassium, magnesium)

Supplement

Recommended to be added to water during the 36-hour fast to manage hunger, maintain energy, and prevent lightheadedness, especially as the body transitions into ketosis.

The speaker mentions adding a pinch of salt or using electrolyte supplements as a key tool during the fast. He notes that as the body shifts to ketones, electrolytes can become imbalanced due to lower insulin levels (which normally help retain sodium), and replenishing them can alleviate symptoms like headaches and fatigue. This makes the 36-hour fast more tolerable and sustains physical and mental performance. The advice is practical and targeted at the later hours when symptoms are most likely.

Maybe even a pinch of salt or some electrolyte supplements or something. That will help you manage the hunger and it can help you keep your energy a little bit higher, especially as you get into the later hours of a fast as you're transitioning into using ketones.

Find Electrolyte

Black coffee and tea during fasting

Practice

Permitted zero-calorie beverages during the monk fast that can curb appetite and provide mild stimulatory benefits without breaking the fast.

The speaker lists black coffee and tea as tools to help get through the fasting day. They are part of his protocol because they do not spike insulin or contain meaningful calories, yet they blunt hunger and provide antioxidants that complement the fast's benefits. He avoids being overly strict, acknowledging that these can make the experience more pleasant and sustainable, but he does not recommend adding milk, sugar, or any caloric additives.

You can have black coffee, maybe some tea. Okay? You don't need to be ridiculously strict. I think you can have like those coffees. You can have those teas.

Find Black
Disclosed sponsorships1speaker disclosed

ButcherBox

Product Sponsored · disclosed

Recommended as the preferred source for grass-fed, grass-finished beef, bison, chicken, scallops, and fish to use in the lean protein refeed step. The speaker highlights its convenience (home delivery) and quality.

DisclosureThe speaker provides a special link and explicitly says he uses their meats to break his fasts. He is likely compensated via affiliate marketing.

The speaker introduces ButcherBox after outlining the refeeding protocol, stating that he personally uses the meat to break his fasts. He emphasizes the grass-fed, grass-finished quality and taste—particularly the bison and beef. He views it as a way to plan ahead for the fast-breaking meal, ensuring that high-quality, lean protein is on hand without having to shop. The recommendation is deeply integrated into the protocol, as he specifically links to ButcherBox for the lean cuts of meat that fit the no-fat, high-protein requirement immediately after the bone broth.

vs alternatives

Implicitly compared to standard grocery store meat that may not be grass-fed/finished or lean enough. The convenience of delivery is also contrasted with the hassle of sourcing specific cuts.

Personal experience

The speaker says: 'I put a link for my preferred protein that I use to break a fast with... ButcherBox... But their beef is the best tasting and their bison is the best tasting bison I've ever had. Super good stuff.'

I put a link for my preferred protein that I use to break a fast with. It's from a company called ButcherBox. All grass-fed, grass-finish, the highest quality meat that I've used in a very long time.

Also said
“Their beef is the best tasting and their bison is the best tasting bison I've ever had.”— Reinforces the personal endorsement and taste claim.
“So, that link is down below that actually gets you a special link that shows you the different cuts that I use and the stuff gets delivered to your doorstep.”— Shows the affiliate nature and practical convenience offer.
Find ButcherBox

Notable quotes

Lines worth pulling out — contrarian, specific, or perfectly phrased

5 items
It's not just about feeling hungry. It's quite literally like an orchestrated response. It's like a metabolic symphony that is perfectly executed.
Memorable metaphor that captures the ordered, adaptive nature of the fasting response, reframing hunger as part of a sophisticated biological program.
The monks knew it best. It's called a monk fast because that 28 to 36-hour peak is when you get the real benefits. And they actually feel they get closer to like enlightenment, right?
Links the scientific benefits of the late-fast window to historical spiritual practices, giving the protocol a compelling narrative hook.
When AMPK is elevated, autophagy kicks in. We're low on fuel. Let's start breaking down other things for fuel. This specific cascade is literally the physiological switch that triggers autophagy.
Succinctly explains the autophagy on-switch in everyday language, making a complex process intuitive.
Yes, protein spikes insulin. So, I want you to be able to get that insulin spike without the fat.
A deliberately counterintuitive move that reframes insulin as a tool, not a toxin, and flips conventional anti-insulin dogma on its head in the context of a fasted state.
The increase in BDNF ends up translating for us normal people into just a little bit more mental clarity, maybe some more focus, improved like memory. So, you might get all that, right? maybe a little more resilience to stressors, like stress isn't going to impact you as much.
Connects the high-level neuroscience of brain-derived neurotrophic factor to relatable, everyday cognitive improvements.

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Topics covered

monk-fast36-hour-fastmetabolic-flexibilitygluconeogenesisketone-productionautophagyampk-mtor-pathwaygrowth-hormoneinsulin-sensitivitybdnfrefeeding-strategybone-brothlean-proteinbutcherboxelectrolytessleep-resetfat-lossmuscle-preservationlight-exercisecircadian-fasting
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