Use the MEDIC framework—Meaning, Error-driven retrieval, Distinctiveness, Importance (emotional salience), Context—to decide what and how to remember.
2
Struggle to recall before checking the answer; error-driven learning hardens memories better than re-reading or passive review.
3
Set an intention by asking “What memory do I want to take away?” and immerse in sensory details (smells, sounds, sights) to create distinctive, lasting memories.
4
End each day by recalling one positive moment—no matter how small—to break mood-congruent recall loops and shift your emotional state.
Protocols
Concrete recipes — what, when, how much, and why
7 items
Error-driven retrieval practice
WhatWhen studying or trying to learn something, actively try to recall the information from memory before checking the correct answer. Then compare your recall to the correct version to fix errors.
WhenDuring study sessions, language practice, learning names, driving to new places, any skill acquisition.
DoseNo set dose; incorporate whenever you would normally re-read or passively review.
For whomAnyone learning facts, skills, directions, languages.
WhyThe brain uses prediction errors to strengthen memory traces; struggling to retrieve and then correcting locks the memory in a more flexible, context-independent way.
CaveatsRequires honest effort and willingness to be wrong; not ideal for purely rote memorization where accuracy is paramount and feedback is absent.
He explained that re-reading or repeating keeps you in a passive mode where your brain never exercises retrieval. By forcing a generated recall attempt, you activate a crummy memory trace, then by contrasting it with the correct answer, the hippocampus triggers a repair process. He gave examples: to remember a name, leave the room, try to visualize the person and recall their name, then later see the person again to correct. For basketball, shoot baskets rather than just thinking about the technique. This method also untethers the memory from a single cue, making it retrievable in new contexts.
Mechanism
Hippocampal pattern completion and separation; dopamine-mediated plasticity during prediction errors; the brain tweaks synaptic weights to align recall with the correct target, similar to how backpropagation works in AI.
If we don't give ourselves a chance to pull up the memory in the first place … I'm not relying on memory in the first place.
Also said
“the more we struggle to try to pull up a memory and if we get the right feedback … it gives our brain a chance to actually stabilize the memory and repair the problems.”— Underlying mechanism.
“you learn a layout of a place better if you drive yourself than if you sit in an Uber.”— Real-life analogy.
“if you look at AI models like chat GPT … they work because of this principle of error driven learning”— External validation.
Sensory focus with intention
WhatBefore or during an experience you want to remember, ask yourself: 'What specific memory do I want to take away?' Then deliberately attend to the sensory details that make that moment unique (smells, sounds, visuals, bodily feelings).
WhenRight as an event begins, or at the start of a day, a trip, or a conversation you value.
DoseA few seconds of meta-cognition at the start; repeated spot-checks during the experience to stay present.
For whomAnyone wanting to preserve personal experiences, travellers, concert-goers, people connecting with loved ones.
WhySetting intention directs attention to distinctive cues, making the memory less confusable with other experiences. Focusing on sensory specifics creates a rich, hippocampus-bound episodic trace.
CaveatsDon’t turn it into obsessive pressure; if you can’t decide, just pick one vivid detail. The goal is presence, not anxiety.
He stressed that passive recording (e.g., taking dozens of photos) often backfires because it reduces immersion in the sensory qualities that make a memory distinctive. Instead, using a camera to capture one uniquely defining detail can enhance memory. He gave the example of being in Hawaii: the humidity, tropical flower smells, bird sounds—those sensory keys transport him back. He suggested that at the end of a day, you could also reflect and intentionally pull up one positive moment, but the proactive intention at the time of experience is most effective.
Mechanism
Engages prefrontal top-down attention control to bias encoding towards salient features; distinctiveness reduces interference between competing memories; sensory details provide powerful retrieval hooks.
Personal experience
He said: 'I say what can I immerse myself in right now that I really want to take away … maybe I'll focus on the sky … or the smells or the sounds … or just kind of check in with my feelings.' This is his new post-book habit.
What I would say is the biggest thing that helps with remembering in a way that will keep get you back into that moment is the sensory details, whatever they are.
Also said
“Ask yourself what you want to take away from this experience in the first place … it's a lot easier to focus on the information that you want to take away … than it is to try to pull it up later on if you did not focus on that information.”— The core metacognitive step.
“when you're mindlessly taking pictures, you're not actually immersed in the details that will give you a distinctive memory.”— Contrast with common mistake.
“I say what can I immerse myself in right now that I really want to take away … maybe I'll focus on the sky … or just kind of check in with my feelings.”— His personal practice.
One positive thing recall
WhatAt the end of the day, force yourself to recall at least one positive detail—even a trivial one, like a good sandwich—to shift your mood and break a negativity spiral.
WhenEvening, before bed or during end-of-day reflection.
DoseOne memory, but can lead to a cascade; no set time.
For whomPeople experiencing a mild bad day or low mood; may not be sufficient for clinical depression but can help milder dysphoria.
WhyMood-congruent memory bias: when you're down, your brain preferentially retrieves negative memories, worsening mood. Deliberately recalling one positive alters the retrieval bias, making additional positive memories accessible and improving emotional state.
CaveatsFor clinical depression, this alone may not work; professional therapy is recommended. Consistency helps but is not required for the acute effect.
He explained the vicious cycle of depression: rumination retrieves more negative memories, deepening the low mood. Cognitive therapy works in part by forcing patients to recall counter-examples. He noted that when he's had a bad day, it takes him a while to find a positive detail, but once he does—like remembering he made a good sandwich—the mood shifts and more good memories come to mind, altering his perception of the whole day.
Mechanism
Dopaminergic and limbic circuitry shift bias; retrieval of a positive memory likely engages ventral striatum and prefrontal areas, lifting mood and opening access to other positive traces via spreading activation.
Personal experience
He said: 'I don't have the discipline to do things consistently, but when I do this, it takes me a while and I'll pull up something dumb like, oh, that you know, I made a good sandwich at lunch … And all of a sudden, I get access to more stuff. It changes the way I feel.'
push yourself to remember just one positive thing, as minor as it could be, at the end of your day. … it takes me a while and I'll pull up something dumb … It changes the way I feel.
Also said
“depression is such a vicious cycle because when you're depressed, you tend to ruminate. And rumination is almost by definition regurgitating memories that are negative that reinforce your feelings at the moment.”— Illustrates why positive recall breaks the cycle.
“The worse you feel, the harder it is to pull up memories that counteract your view of the world at a given time.”— Highlights the need for deliberate counter-bias.
“if you're not clinically depressed, it's a lot easier to pull yourself out of it by pushing yourself to remember just one positive thing.”— Clarifies the scope.
Single-tasking during memorable moments
WhatWhen you want to form a lasting memory, put your phone away, turn notifications off, and avoid mental distractions like thinking about email or social media.
WhenDuring any experience you value—dinner with friends, a concert, a holiday, even work tasks you need to recall.
DoseAs long as the event lasts; ideally create a habit of not checking devices during social or meaningful activities.
For whomAnyone, particularly in the smartphone era.
WhyMultitasking (or even the temptation of it) saps attention and prevents the deep processing needed for distinctive, context-rich memories.
CaveatsComplete removal may not always be possible; even turning the phone screen-down or putting it in another room reduces cognitive load.
He listed memory blockers: stress, fatigue, illness, depression, and multitasking, calling multitasking 'the major malady of the modern age'. Even if you resist checking your phone, the mere thought of it can pull attention away from the present, sabotaging memory formation. He admitted that he himself checks email too much, underscoring that it's a common but avoidable trap. The goal is to protect the quality of the experiencing self's input.
Mechanism
Prefrontal resource competition: dividing attention weakens encoding in the hippocampus and reduces the distinctiveness of the memory trace; strong memory depends on focused, unbuffered processing.
Personal experience
He said: 'I have checked email way too many times today … those are things that are not the stuff that I want to remember later on.' He framed it as wasted time that generates no desired memories.
Multitasking is probably the major malady of the modern age. … if you want to remember this moment, don't keep looking at your phone.
Also said
“the more tempted you are to do these things even thinking about it can be enough to sap your attention and get you out of that moment that you want to remember later on.”— Nuance that temptation alone impairs.
“I have checked email way too many times today. … those are things that … for the most part that's wasted time in the sense that it generated no memories that I will want to carry with me.”— Personal confession.
Return to the original context
WhatIf you forget why you entered a room or can't recall a detail, physically or mentally return to the environment where the memory was formed; the shift in context will often unlock the memory.
WhenWhenever you have a 'Why did I come in here?' moment, or when trying to remember a past event.
DoseA brief walk back to the previous room; or mentally visualising the original context.
For whomEveryone, daily memory slips.
WhyThe hippocampus indexes memories by time and place; stepping back through the boundary between contexts reactivates the relevant neural ensemble.
CaveatsWorks only if the context is available; may not work for deeply encoded memories if the trace has decayed.
He gave the classic example of walking to the kitchen and forgetting why, then walking back to the office and instantly remembering. He explained that boundaries between rooms act as event markers, and crossing them clears the previous context. This is part of the 'context' in his MEDIC acronym: a change in place separates memories. He also used the pandemic example: being stuck in one context made memories blur together, causing a sense of lost time.
Mechanism
Hippocampal place cells and temporal sequence reactivation; moving back through a doorway acts as an event boundary, re-cuing the previous neural state.
you walk into the kitchen and you can't remember why you went there … then you walk back to whatever room you went from. And now it all of a sudden pops in your head.
Also said
“my memory for what I wanted to do was in say this room which is my home office but then when I get to the kitchen I'm in a different context. My mind is switched over to a different place.”— Explanation of context shift.
“these boundaries between the rooms act as shifts in our context that make it harder to remember things in the past.”— Generalisation to event boundaries.
Ask 'Will my future self care?'
WhatWhen you stress about forgetting something, pause and ask whether your future self, 10 years from now, would care if you forgot it. Use the answer to decide how much mental energy to invest.
WhenDuring or after an experience, or when feeling guilty about not remembering enough.
DoseA quick mental question; can become a habit.
For whomPeople prone to memory guilt, over-documenters, perfectionists.
WhyMemory is selective and limited; constantly chasing perfect recall creates guilt and distraction. Accepting that most experiences don't need to be retained frees attention for the ones that do.
CaveatsSome experiences might matter in unexpected ways; but on average, the filter aligns with memory's evolved function to keep only what is likely to be useful.
He linked this to the idea of packing a suitcase for a trip: you pack only what you'll need, not everything you own. The brain does the same—it selects memories based on future utility. The remembering self is a tiny fraction of the experiencing self, and that's a feature, not a bug. He argued that trying to memorise more creates guilt, but the goal is to remember better, not more. The filter helps you invest in the memories your future self will actually value, like a holiday with loved ones rather than the email you just read.
Mechanism
Metacognitive reframing that engages prefrontal control to override hippocampal encoding bias, reducing unnecessary consolidation attempts.
Personal experience
He said: 'ask yourself … 10 years later, will my future self care that I forgot this? No.' He implied he applies this to his own life.
there's a lot that we forget that you can look and ask yourself … 10 years later, will my future self care that I forgot this? No.
Also said
“we're blessed with this incomplete memory because what we remember tends to be what we need.”— Foundational belief.
“to some extent, a holiday is an investment in memories … on the other hand, there's a lot that we forget that you can ask yourself … will my future self care? No.”— Practical application.
Micro-novelty practice
WhatIn everyday routines, consciously look for small, novel details—a different cloud shape, a stray thought, a new sound—to engage curiosity and trigger dopamine-driven plasticity.
WhenAny time, especially during repetitive commutes or tasks.
DoseA few moments of deliberate attention; can be embedded in daily mindfulness.
For whomAnyone feeling their days blend together, wanting to slow subjective time, or boost learning capacity.
WhyNovelty and surprise generate prediction errors, releasing dopamine which promotes memory consolidation; even in familiar settings, micro-novelties exist if you attend to them.
CaveatsRequires conscious effort; might not produce massive effects but adds up.
He argued that novelty doesn\u2019t require completely new experiences; the brain is always making predictions, and tiny violations—like a bird song you never noticed on your walk—create prediction errors that stimulate curiosity and memory. He tied this to mindfulness practices that train attention to details, thereby generating distinctive memories even in repetitive contexts. This also slows the subjective passage of time by creating more memory anchors.
Mechanism
Dopaminergic midbrain and hippocampus; prediction errors signal ‘something new,’ increasing plasticity and encoding, consistent with error-driven learning.
I guarantee you that almost anything you do can be associated with some novelty. But you have to be curious and look for it and not assume … that your predictions are right.
Also said
“the world is always changing. Our brains are always changing. but often we just don't notice it.”— Rationale for micro-novelties.
“if you take like meditative practices like mindfulness, a big part of these practices is attuning yourself to what's new and that creates these prediction errors in your brain. It stimulates curiosity and will give you better memories.”— Connects to established practice.
What's new
Personal practice updates, fresh positions, predictions
6 items
MEDIC mnemonic for memory formation factors
Dr. Ranganath introduced a new acronym MEDIC—Meaning, Error, Distinctiveness, Importance, Context—that distills the key drivers of whether an experience gets encoded into episodic memory.
Why this matters: It stringifies half a dozen memory principles into a single sticky heuristic; he admitted he only recently created it after years of explaining memory.
Background
Previously, he would rattle off the factors piecemeal; the mnemonic makes them accessible for everyday use.
He unpacked each letter: Meaning: tie new information to existing knowledge (e.g., soccer stats for a fan). Error: struggling to retrieve a memory and then correcting it prompts the brain to repair and strengthen the memory trace—a principle also behind AI training. Distinctiveness: our memories compete, so attending to unique features of an experience prevents confusion. Importance: emotionally arousing events—anything triggering dopamine, noradrenaline, serotonin, cortisol—get rapid consolidation; it\u2019s not what you rationally think you should remember but what your evolution-tuned brain deems salient. Context: episodic memories are glued to a time and place; the hippocampus files them that way, which is why returning to a context can unlock forgotten moments. He noted these factors interact to determine a memory\u2019s fate.
Personal experience
He confessed that it took him forever to come up with the acronym, and he’s now relying on it himself to remember the factors.
I actually came up with an acronym for this after talking about memory for a long time and it took me forever to realize that I could come up with a pneummonic to help me remember these things which is medic. … It did come to me. The pneummonic helped.
Also said
“Meaning is a really good way to lock in new information by being able to tie what you're trying to learn with stuff you already know.”— Illustrates the Meaning factor with concrete mechanism.
“So error is basically the fact that the more we struggle to try to pull up a memory and if we get the right feedback what will happen is is it gives our brain a chance to actually stabilize the memory and repair the problems.”— Explains the counterintuitive Error principle.
“distinctiveness means that essentially our memories are competing with each other. … If there's some way I can attend to the features that make you different … now I will have a distinctive memory.”— Clarifies distinctiveness and its role in avoiding interference.
“dopamine … gets you revved up and it promotes plasticity. It allows these memories to rapidly consolidate.”— Biological basis for the Importance factor.
Error-driven learning strengthens memory more than passive review
Contrary to intuitions, letting yourself struggle to recall and then receiving correct feedback engages the hippocampus to repair and stabilise the memory trace far more effectively than repeated reading or listening.
Why this matters: Many study habits rely on re-reading; this reveals an active retrieval-and-correction cycle is the biologically preferred route to robust memory.
Background
Standard advice often promotes rote repetition; his lab\u2019s models of memory predict that prediction errors during retrieval trigger plasticity.
He likened the brain to an AI like GPT, which learns by predicting the next token and correcting when wrong. When you try to retrieve a memory—say, a name—you generate a partially correct pattern; by then checking the right answer (a video, a source), your brain compares the two and tweaks the connections just enough to bridge the gap. This not only improves accuracy but also loosens the memory\u2019s dependence on a single context, making it recallable in more situations. He gave the example of learning a language: blindly repeating a phrase keeps you from ever using your own flawed memory, so you never force the brain to update it. In contrast, throwing yourself into a conversation where you must retrieve words and then being corrected by a native speaker yields far better retention. The same principle applies to driving yourself to a new location vs. following an Uber; self-navigation forces retrieval and error-correction, generating a richer mental map.
If we don't give ourselves a chance to pull up the memory in the first place … I'm just kind of like trying to read this word over and over and over again, but I always have the right answer. So, I'm not relying on memory in the first place.
Also said
“the more we struggle to try to pull up a memory and if we get the right feedback … it gives our brain a chance to actually stabilize the memory and repair the problems.”— Core mechanism.
“you learn a layout of a place better if you drive yourself than if you sit in an Uber. Because you're actively trying to generate stuff for memory and then finding, oh wait, I was wrong.”— Real-world example of error-driven spatial learning.
“if you look at AI models like chat GPT … they work because of this principle of error driven learning where the model tries to predict … and if it gets it wrong then it tweaks just the connections in the model.”— Analogy that anchors the mechanism in machine learning.
Intention before experience boosts memory encoding
Asking yourself what you want to take away from a moment—e.g., a conversation, a trip—primes your brain to focus on those specific features, dramatically improving later recall.
Why this matters: Simple meta-cognitive nudge that most people never use; he now adopts it after reflecting on his own memory research.
Background
Memory is inherently selective; setting an intention exploits that selectivity instead of fighting it.
He pointed out that many people passively assume they\u2019ll remember everything, then feel guilty when they don\u2019t. By explicitly deciding what\u2019s worth carrying forward, we direct our attention to the cues that will later serve as retrieval hooks. He suggested, for instance, on a holiday, taking a moment at the end of the day to intentionally reflect on one positive event; that act not only brings the event to mind but also reinforces it so it becomes part of your narrative. The flip side is that passive recording (e.g., snapping endless photos) often produces poorer memory because you\u2019ve outsourced attention to the camera without encoding distinctive details.
Personal experience
He shared that before writing his book he rarely did this, but now he actively asks himself ‘What memory do I want to take away?’—and then focuses on sensory specifics like the sky, smells, or his feelings at that moment.
Ask yourself what you want to take away from this experience in the first place … it's a lot easier to focus on the information that you want to take away … than it is to try to pull it up later on if you did not focus on that information.
Also said
“if you know memories, your memory is going to be incomplete. Ask yourself what you want to take away … how often do we really ask ourselves, what's the memory I want to take away from this experience? I would bet you almost never.”— Underscores how rarely it's done.
“I say what can I immerse myself in right now that I really want to take away … maybe I'll focus on the sky and what it looks like right now or the smells or the sounds … or just kind of check in with my feelings.”— Personal technique of focusing on sensory details.
“when you're mindlessly taking pictures, you're not actually immersed in the details that will give you a distinctive memory. … all we get out of it is a recording that most of us never go back to.”— Contrast with passive recording.
Emotions turn up memory's contrast, not its volume
Intense emotions don\u2019t make you remember everything equally; they sharpen the most salient, threat-relevant details while often reducing memory for peripheral information.
Why this matters: Counters the folk belief that ‘emotional memories’ are simply stronger across the board; it\u2019s a selectivity principle.
Background
Common assumption: strong emotions make memories more vivid overall. Dr. Ranganath clarifies that dopamine, noradrenaline, cortisol increase plasticity but bias encoding toward the emotionally loud parts.
He gave the example of a traumatic event: you will remember the traumatic core—the weapon, the attacker, the fear—far better than the colour of the carpet. He extended this to positive arousing experiences like surfing or snowboarding: you recall the most exhilarating wave, not the conversation on the beach. Calming positive emotions may not get the same chemical boost because they don\u2019t trigger the same catecholamine surge. This ‘contrast’ effect means emotional memories can feel exceptionally vivid but are actually highly edited, which has implications for eyewitness testimony and personal narratives.
Emotions don't turn up the volume in memory or the brightness in memory so much as they turn up the contrast. So they help you remember certain things more than others and they give us a sense of vividness but not necessarily that context.
Also said
“if you have a traumatic experience, you'll remember the things that were especially traumatic about it as opposed to the color of the carpet or … the rabbit that was in the background.”— Concrete illustration.
“these emotionally intense moments where you get these chemicals released in your brain they don't turn up the volume … they turn up the contrast.”— Restatement of the core metaphor.
“when you have positive experiences that are kind of calming, we don't know as much about them. … maybe if it's relaxing, it's not going to be the same chemicals released in the brain that are going to promote these memories.”— Nuance about calming positive states lacking the same consolidation boost.
Highly superior autobiographical memory is a burden, not a gift
Individuals who remember nearly every day of their lives often describe it as torture, and their daily functioning is no better than average, challenging the dream of unlimited memory.
Why this matters: Defies the tech‑fuelled fantasy of perfect recall; validates forgetting as adaptive.
Background
Popular culture celebrates extraordinary memory; some people with HSAM are studied. Dr. Ranganath references interviews where they call it tormenting because irrelevant and negative memories constantly resurface.
He argued that forgetting is a feature—our brains evolved to pack only what we need for the journey of life. Packing everything would be like carrying all your belongings on vacation; you\u2019d be weighed down. HSAM individuals often get stuck in loops of trivial or painful recollections. He also noted that structural brain differences in HSAM are surprisingly subtle, and these people don\u2019t excel at school or life, which implies that raw memory ability isn\u2019t the bottleneck for success. Expertise in a domain—like LeBron James\u2019s game memory—comes from deeply built knowledge structures, not a magic trait.
If you read descriptions, many of these people talk about it as torture. … they are often plagued by memories. at best it's irrelevant stuff and at worst it's the stuff that is minor and negative but it just comes back to them over and over again.
Also said
“we're blessed with this incomplete memory because what we remember tends to be what we need.”— Positive reframing of forgetting.
“you can look at people with … severely deficient autobiographical memory … Yet you look in real life and the highly superior and the severely deficient people, they're functioning at equal levels.”— Shows memory vividness doesn't predict life function.
“LeBron has this extraordinary memory for basketball games. … what seems like this incredibly confusing array of people … He's able to just grab it and put it in a little compartment because he's already seen it before.”— Domain expertise example reinforcing that memory is pattern-based, not total recall.
Memory shapes the subjective speed of time
When days feel slow but weeks vanish, as during lockdowns, it\u2019s a memory phenomenon: monotonous context produces few distinct memories, leaving a blank retrospective time void while the present drags.
Why this matters: Explains a pandemic-wide temporal illusion using memory science.
Background
People reported contradictory time experiences in lockdown; this paradox is resolved by memory\u2019s dual role in moment-by-moment awareness and retrospective estimation.
He detailed his class survey during lockdown: 98% felt individual days crawled by, yet at week\u2019s end everyone said the weeks flew. The reason: staying in the same context (home) all day generated few distinct episodic memories, so looking back, time seemed empty and fast. Conversely, a day rich in novel events feels long in hindsight and short in the moment. He tied this to the hippocampus\u2019s contextual indexing—without varied contexts, memory blurring creates a \u2018temporal void\u2019. He also mentioned memory disorder patients who can\u2019t answer the date because their last anchored memory is stuck years in the past.
Personal experience
He recounted asking his students during the pandemic and seeing the startling split in responses.
During the pandemic … I asked them … do you feel like the days are going faster or slower … Overwhelming majority said … slower on a 24‑hour basis … but then … everybody said that the weeks were going by faster. … how does time move more slowly in a day but disappear in a week? … you haven't been accumulating all these memories that would give you a sense of time passing.
Also said
“you look back and it just feels like the time went by and disappeared because you have effectively lost that time because you can't remember it”— Consequences of context-poverty on autobiographical memory.
“if you ask people with memory disorders what date is it? They won't be able to tell you because their last memory of a time in a date was the time that they had … a good memory.”— Extreme case linking memory to temporal orientation.
Disclosed sponsorships2speaker disclosed
Dr. Ranganath's memory book (referred to but not named)
Book Sponsored · disclosed
Throughout the interview, he references insights from 'my book' and mentions that he wrote about LeBron James and other topics in it. It is the source for his personal stories and the MEDIC framework.
DisclosureHe is the author
While he doesn't give the title, he encourages listeners to learn more; the book is likely the one he published recently that delves into the neuroscience of memory and practical strategies. He says most of the problems he writes about are his daily experiences, so it blends science with personal narrative.
I mentioned him in my book, and I also did an interview with the NBA about this.
Also said
“Most of these problems that I write about in the book are my daily experiences.”— Shows the book's personal grounding.
Lines worth pulling out — contrarian, specific, or perfectly phrased
4 items
We're blessed with this incomplete memory because what we remember tends to be what we need.
Flips frustration about forgetting into an evolutionary gift.
Memory is probably not important for the reason people think it is. … it's absolutely central to helping us understand the present … and to be able to plan and imagine possible futures.
Redefines memory’s true purpose beyond nostalgia.
The more you struggle, the better it is, information will stick.
Counterintuitive, pithy anchor for error-driven learning.
Your dog's going to wake up tomorrow and be 2% faster because it's practiced it during its sleep.
Humorous illustration of sleep’s role in motor memory consolidation.
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Educational summary of the cited expert source — not medical advice. Open the source recording linked above and consult a qualified physician before acting on any protocol.