Gut Barrier Integrity Trio
DeLauer positions the gut as the primary gateway for microplastic entry, citing studies that smaller particles absorb easier. He acknowledges that stool can contain microplastics, so if fewer enter the bloodstream, more may end up in stool. The glutamine dose (every other day) is his empirical suggestion; he doesn't provide a study to back it but frames it as a practical measure. He also emphasizes that gut inflammation, often caused by emulsifiers like polyorbates, can further compromise the barrier, so this protocol is part of a larger gut‑centric strategy.
The intestinal epithelium relies on tight junction proteins to regulate paracellular permeability. Glutamine is a primary fuel for enterocytes, supporting cell turnover and junction protein expression. Collagen provides amino acids like glycine and proline that are used to repair the gut lining. Bone broth supplies glycosaminoglycans and additional collagen. Together they promote the integrity of the mucosal barrier, physically limiting the passage of small particles like microplastics.
We want to consume things like collagen. We want to consume things like bone broth. We want to consume 3 to five grams of glutamine probably every other day.

