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Hubert Czerniak - NIACYNA cz. 1 z 4 / Witamina B3 bez tajemnic / Niesamowite i skrywane właściwości
~15 min
Brief odcinka·YouTube

Hubert Czerniak - NIACYNA cz. 1 z 4 / Witamina B3 bez tajemnic / Niesamowite i skrywane właściwości

Hubert Czerniak
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TL;DR

Cztery rzeczy, które stracisz, jeśli nie obejrzysz

4 elementów

TL;DR

Cztery rzeczy, które stracisz, jeśli nie obejrzysz

4 elementów
1

Book 'Niacyna w leczeniu' reveals niacin's vast health benefits, from cholesterol reduction to schizophrenia treatment.

2

Immediate-release nicotinic acid in doses of 1000–6000 mg three times a day dramatically improves lipid profiles by preventing HDL reuptake.

3

Slow-release niacin is dangerously hepatotoxic – 52% of patients in one study developed liver problems versus 0% with immediate-release.

4

Schizophrenia may be a niacin-deficiency disease, with high-dose vitamin B3 achieving up to 90% remission contrary to conventional medicine's 0%.

Protokoły

Konkretne przepisy — co, kiedy, ile i dlaczego

3 elementów

High-dose immediate-release niacin for lipid management

CoTake nicotinic acid (not niacinamide, not SR) starting with low doses and titrating up to 1,000–6,000 mg three times daily.
KiedyWith meals, split into three times/day.
Dawka3 x 1,000–6,000 mg/day (3,000–18,000 mg total); start low and increase gradually.
Dla kogoIndividuals with dyslipidemia, high cardiovascular risk.
DlaczegoNiacin blocks liver reuptake of HDL, lowering total cholesterol, LDL, VLDL, CRP, and raising HDL. Only immediate-release nicotinic acid achieves this without liver toxicity.
ZastrzeżeniaCauses prostaglandin-mediated flush (harmless but uncomfortable); to mitigate, start with low dose, may take with aspirin or at night. Avoid slow-release forms due to severe hepatotoxicity. Do not substitute with niacinamide or inositol hexanicotinate if lipid improvement is desired.

The speaker contrasts the effects of niacin forms. Immediate-release nicotinic acid is effective and safe for the liver, while slow-release niacin, designed to avoid flush, concentrates in the liver and becomes toxic. He cites McKenney's 30-week trial where 0/23 patients on immediate-release had liver issues vs 52% on SR. He also mentions the UC Irvine experiment that illuminated the mechanism. He emphasizes that pharmaceutical companies created patented forms like inositol hexanicotinate to profit, but they are less effective or dangerous.

Mechanizm

Niacin affects the liver's handling of lipoproteins. A study at UC Irvine showed that nicotinic acid prevents the re-uptake of HDL into liver cells, likely by inhibiting a surface receptor or pathway, resulting in higher circulating HDL and lower LDL/VLDL. This is independent of the flush, which is caused by release of prostaglandins from skin mast cells.

grupa doktora mckenia podawała przez 30 tygodni dawki od 500 do 3000 mg dziennie u żadnego z 23 pacjentów przyjmujących niacynę szybko działającą nie stwierdzono problemową wątrobowych natomiast aż 12 z 23 przyjmujących niacynę SR czyli 52% ucierpiało z powodu hepatotoksycznego działania preparatu

Powiedział też
“ta traktowana niacyną nie wpuszcza hdl-u do komórki wątrobowej najprawdopodobniej z tego powodu dochodzi do poprawy profilu lipidowego”— Mechanism: HDL not reabsorbed.
“hekso nikotynian inozytolu... nie obniża cholesterolu w takim stopniu jak kwas nikotynowy”— Comparison showing inferiority of patented form.

High-dose niacin for schizophrenia

CoAdminister gram-level doses of niacin (vitamin B3) daily under medical supervision to correct the biochemical deficit underlying schizophrenia.
KiedyContinuous daily supplementation; dosage adjusted to individual need.
DawkaNo specific dose provided in this transcript; Hoffer's typical range was 3–18 g/day.
Dla kogoIndividuals diagnosed with schizophrenia, especially those not helped by standard antipsychotics.
DlaczegoSchizophrenia is posited as a niacin-dependency disease due to a genetic or acquired increased requirement. High-dose niacin corrects the deficiency, resolving hallucinations and thought disorder.
ZastrzeżeniaHigh doses can cause flush (with nicotinic acid) or nausea (with niacinamide). Must be supervised by a practitioner knowledgeable in orthomolecular medicine. Regular liver function monitoring is prudent, but immediate-release niacin is low risk compared to SR.

The speaker presents Hoffer's work showing 90% recovery rate in schizophrenics treated with niacin, contrasted with 0% using conventional neuroleptics. He describes schizophrenics as highly perceptive individuals whose brains break down under niacin deficiency, leading to disordered reality interpretation. Standard drugs sedate them into a zombie state, while niacin addresses the root biochemical cause. This is part of the orthomolecular paradigm that sees mental illness as a biochemical individuality issue. The speaker underscores that this knowledge is ignored because niacin cannot be patented.

Mechanizm

Niacin is a precursor to NAD/NADP, crucial for energy metabolism and neurotransmitter synthesis. In schizophrenics, a biochemical inefficiency in the kynurenine pathway or excessive oxidation may deplete niacin, leading to altered dopamine/serotonin function. High doses restore normal redox balance and neurotransmitter function.

schizofrenicy wymagają dużej dawki witaminy PP niacyny i są praktycznie w 90% wyleczalni natomiast medycyną klasyczną jeżeli się posługujemy 0% wyleczalności

Powiedział też
“daje im się farmakologie która ich przymula że chodzą jak zombie praktycznie są straceni dla społeczeństwa”— Critique of standard treatment.
“Abram Hoffer zajmował się przez wiele lat leczeniem schizofrenii wydał książkę gdzie pisze że choroby psychiczne to zazwyczaj choroby o podłożu biochemicznym a schizofrenia to nic innego jak zależność od dnia cyny”— Hoffer's biochemical basis for schizophrenia.

Niacin preloading for carcinogen resistance

CoPre-treat cells with high-dose niacin to enhance resistance to carcinogens; translational use would involve chronic high-dose niacin supplementation.
KiedyProphylactic, ongoing.
DawkaNo human dose specified; in vitro high-dose niacin exposure.
Dla kogoIndividuals at high risk of cancer or exposed to carcinogens; conceptual protocol based on cell studies.
DlaczegoNiacin supports mitochondrial health and cellular energetics, making cells less likely to undergo the deranged mitotic reset that leads to cancer when exposed to toxins.
ZastrzeżeniaHuman in vivo data lacking; theoretical. High-dose niacin side effects must be managed.

The speaker draws a direct line from mitochondrial dysfunction to cancer, explaining that transferring mitochondria from cancer cells induces cancer in normal cells. He argues that supplying optimal nutrients, especially niacin, allows the body's detox pathways (e.g., cytochrome P450) to manage xenobiotics and maintain mitochondrial integrity. This positions high-dose niacin as a general anti-cancer prophylactic, though clinical translation is still experimental. The 90% slowing of cancer growth in niacin-treated cells underscores the potential magnitude of the effect.

Mechanizm

Mitochondria, the cell's energy factories, when overloaded with toxins, can spark uncontrolled division as a survival reset. Niacin, as NAD precursor, boosts oxidative phosphorylation and antioxidant capacity, stabilizing mitochondria and preventing the carcinogenic switch. The study mentioned showed 90% slower cancer development in niacin-treated cells exposed to carcinogens.

Badania wykazały że ludzkie komórki które były poddane działaniu wysokich dawek niacyny a następnie czynnika rakotwórczego były bardziej odporne na ten czynnik rakotwórczy rak rozwijał się o 90 wolniej

Powiedział też
“przeszczepienie mitochondrium z komórki nowotworowej do zdrowej wywołuje nowotwór w tej dotychczasowej komórce”— Mitochondrial etiology of cancer.

Co nowego

Zmiany w osobistej praktyce, świeże stanowiska, prognozy

5 elementów

rediscovery of niacin's hidden benefits after reading the Hoffer/Foster/Saul book

The speaker initially disbelieved claims about niacin but after reading the comprehensive book, he now views it as a wonder nutrient suppressed because it cannot be patented.

Dlaczego to ważne: This personal shift underscores the tension between unpatentable natural substances and pharmaceutical interests.

Kontekst

Niacin (vitamin B3) has been used for almost a century, but modern education often overlooks its broad therapeutic effects. The speaker was skeptical until encountering a detailed compilation of evidence.

The speaker describes finding the book 'Niacyna w leczeniu' (Niacin in Treatment) by Abram Hoffer, Harold Foster, and Andrew Saul. He explains that the truth about niacin is hidden because it can't be patented, and mainstream medicine focuses on patentable drugs. He contrasts the public's ignorance with the potential of orthomolecular therapy that uses high doses of vitamins and minerals. He notes that even Linus Pauling, a Nobel laureate, was ridiculed for promoting vitamin C, yet his advocacy coincided with a decline in cardiovascular mortality. The speaker adopts the view that many psychiatric and metabolic disorders have a biochemical basis that niacin can address.

Osobiste doświadczenie

Last week, a book came into my hands, a bestseller in my opinion, by three authors: Hoffer, Foster, and Dr. Andrew Saul... niacin works miracles. I didn't believe until I rediscovered it. I invite you to this episode.

ostatnio wpadła mi w ręce książka niacyna w leczeniu dzieło trzech tenorów... działa cuda nie wierzyłem aż odkryłem to na nowo

Powiedział też
“problem stwarza to czego nie wiemy... jednak naszym prawdziwym problemem jest to co wydaje nam się że wiemy a co okazuje się nieprawdą”— Highlights the theme of hidden truth due to patent issues.

niacin forms and their distinct effects

Nicotinic acid powerfully improves lipid profile and causes flush; niacinamide does not improve lipids nor cause flush but causes nausea at gram doses; inositol hexanicotinate is patented, less effective than nicotinic acid; slow-release niacin is highly toxic to the liver.

Dlaczego to ważne: This detailed comparison is rarely taught, explaining why many clinicians avoid niacin or choose inferior forms.

Kontekst

Vitamin B3 exists as nicotinic acid, niacinamide, inositol hexanicotinate, and slow-release formulations. Conventional medicine often prescribes slow-release niacin to avoid the 'flush' side effect, unaware of its hepatotoxicity.

The speaker cites studies comparing forms: on liver cells, nicotinic acid blocked HDL reuptake, improving lipid profile. Niacinamide had no such effect and caused nausea in gram doses. Inositol hexanicotinate (6 niacin molecules on inositol) lowered cholesterol but less effectively and is patented, making it expensive and prescription-only. Slow-release niacin was investigated; Henkin et al. found 8/15 patients developed liver toxicity, whereas 0/67 on immediate-release did. McKenney's group gave 500–3000 mg/day for 30 weeks: 0/23 immediate-release had liver issues versus 12/23 (52%) on slow-release. The speaker emphasizes the need to avoid slow-release niacin.

hekso nikotynian inozytolu czyli taka forma witaminy PP gdzie 6 cząstek niacyny jest zaczepionych na cząstce inozytolu ma co prawda cechy obniżania cholesterolu... ale nie obniża cholesterolu w takim stopniu jak kwas nikotynowy

Powiedział też
“henkin i współpracownicy wykazali 8 przypadków zapalenia wątroby wśród 15 osób przyjmujących niacynę tą formę SR natomiast ani jednego w grupie 67 osób przyjmujących zwykłą szybko działającą niacynę”— Quantified hepatotoxicity of slow-release niacin.
“grupa doktora mckenia podawała przez 30 tygodni dawki od 500 do 3000 mg dziennie u żadnego z 23 pacjentów przyjmujących niacynę szybko działającą nie stwierdzono problemową wątrobowych natomiast aż 12 z 23 przyjmujących niacynę SR czyli 52% ucierpiało z powodu hepatotoksycznego działania preparatu”— Further data showing severe liver damage risk with SR form.

orthomolecular medicine and the suppression of niacin research

The speaker argues that effective niacin research is deliberately not indexed in MEDLINE because it threatens drug patents, and highlights Linus Pauling's orthomolecular concept and Hoffer's schizophrenia cures.

Dlaczego to ważne: Contrarian stance: the medical establishment actively hides evidence for high-dose vitamin therapy.

Kontekst

Orthomolecular medicine, coined by Linus Pauling in 1968, uses natural substances in optimal amounts to correct biochemical imbalances. Many psychiatrists, like Abram Hoffer, reported high success rates treating schizophrenia with niacin, yet this work is absent from mainstream databases.

The speaker points out that MEDLINE, funded by taxpayers, contains no papers from orthomolecular psychiatry despite the existence of numerous published articles. He claims that the drug industry suppresses this information because niacin cannot be patented. He references Linus Pauling, who noted that about 2.5% of the population has unique nutritional needs and may be geniuses, including schizophrenics. The speaker criticizes conventional psychiatry for drugging schizophrenics into a zombie state instead of correcting underlying biochemical deficiencies. He stresses that niacin's broad effects are dismissed when attributed to one vitamin, whereas a multi-purpose drug is celebrated.

wiele artykułów lekarzy i naukowców działających na tej płaszczyźnie pisało pracę opisywali swoje badania jednak Madeline że taka platforma Gdzie możemy znaleźć pracę naukowe w medline nie możecie nic znaleźć a przecież jest to baza danych baza prac naukowych które są opłata baza jest opłacana z pieniędzy podatników

Powiedział też
“prawda jest ukryta gdzieś głęboko dlaczego bo nie można jej opatentować”— Succinct reason for suppression.

schizophrenia as a niacin-deficiency biochemical disorder

Schizophrenia may be a biochemically driven condition responsive to high-dose niacin, with up to 90% cure rate versus 0% with standard drugs. Schizophrenics are physiognomically distinct, often highly intelligent and aging well but suffering from acute perceptual disturbances under niacin deficiency.

Dlaczego to ważne: This radical reinterpretation of schizophrenia challenges the dominant psychiatric model and suggests a curative nutritional therapy.

Kontekst

Abram Hoffer pioneered high-dose niacin therapy for schizophrenia in the 1950s. Mainstream psychiatry views schizophrenia as a chronic brain disorder managed by antipsychotics, with no cure.

The speaker explains that schizophrenics have a higher biochemical demand for niacin; when deficient, they experience hallucinations and interpret reality abnormally. In contrast to the standard pharmacological approach that renders patients catatonic and socially lost, high-dose niacin addresses the root cause. He describes schizophrenics as 'iPhone compared to old Nokia'— their brains are highly organized and capable of seeing connections others miss. Physically, they tend to age gracefully and are more eloquent. The speaker asserts that conventional medicine offers 0% cure, whereas with niacin, around 90% can recover. This aligns with the orthomolecular view that mental illness often has a nutritional/biochemical origin.

schizofrenicy wymagają dużej dawki witaminy PP niacyny i są praktycznie w 90% wyleczalni natomiast medycyną klasyczną jeżeli się posługujemy 0% wyleczalności

Powiedział też
“schizofrenicy są grupą ludzi która jest inteligentna widzi dużo kojarzy dużo więcej niż my to jest porównanie iPhone'a do starej Noki”— Illustrates the cognitive superiority narrative.
“przy deficytach niacyny mają strasznie skomplikowane Życie”— Link between deficiency and pathology.

mitochondrial malfunction as the root of cancer and cellular reset

Cancer arises when mitochondria, overwhelmed by toxins and nutrient lack, trigger a mitotic reset as a survival mechanism, leading to uncontrolled division of immature cells. High-dose niacin increases cell resistance to carcinogens.

Dlaczego to ważne: Frames cancer as a metabolic stress response, suggesting nutritional intervention can reverse early-stage transformation.

Kontekst

Standard oncology views cancer as genetic mutations leading to uncontrolled growth. The speaker adopts a metabolic/mitochondrial theory popularized by Thomas Seyfried and others.

The speaker uses the analogy of a frozen laptop requiring battery removal for reset. When mitochondria, the cell's powerhouse with its own DNA (inherited maternally), face excessive toxins and insufficient nutrients, they falter and initiate a mitotic division to reset. However, if the toxic environment persists, this leads to rapid, undifferentiated cell division – cancer. He cites research showing that transferring mitochondria from a cancer cell into a healthy cell causes cancer, proving the mitochondrial origin. He then notes that pre-treating cells with high niacin made them 90% more resistant to carcinogens, slowing cancer development drastically. This suggests niacin supports mitochondrial resilience, preventing the carcinogenic switch.

przeszczepienie mitochondrium z komórki nowotworowej do zdrowej wywołuje nowotwór w tej dotychczasowej komórce

Powiedział też
“Badania wykazały że ludzkie komórki które były poddane działaniu wysokich dawek niacyny a następnie czynnika rakotwórczego były bardziej odporne na ten czynnik rakotwórczy rak rozwijał się o 90 wolniej niż ta grupa tkanek która nie miała kontaktu z wysokim poziomem niacyny”— Direct evidence for niacin's anticancer effect in vitro.
“komórka przed śmiercią ratuje się tworząc reset a więc podział mitotyczny dochodzi do szybkiego podziału i teraz im bardziej jesteśmy za toksycznymi tym bardziej dochodzi do szyb tym szybciej dochodzi do podziałów komórki jeszcze niedojrzałej... to jest nowotwór”— Mechanistic explanation of cancer as mitochondrial reset.

Rekomendacje

Produkty, suplementy i narzędzia wymienione w odcinku

3 elementów

Niacyna w leczeniu (Niacin in Treatment) by Abram Hoffer, Harold Foster, Andrew Saul

Książka

The speaker discovered this book and it profoundly changed his view on niacin. He considers it a bestseller that unearths hidden therapeutic properties of vitamin B3.

The book is a comprehensive work on niacin therapy covering its history, uses in schizophrenia, cardiovascular disease, and other conditions. It is authored by pioneers of orthomolecular medicine: Abram Hoffer, who treated thousands of schizophrenics with high-dose niacin; Harold Foster, a medical geographer; and Andrew Saul, a prominent orthomolecular educator. The speaker references it as the catalyst for his own re-evaluation of niacin, noting that the information inside contradicts mainstream medical teachings and is suppressed due to patent issues.

Osobiste doświadczenie

Yesterday a book fell into my hands... a bestseller in my opinion... niacin works miracles. I didn't believe until I rediscovered it.

ostatnio wpadła mi w ręce książka niacyna w leczeniu dzieło trzech tenorów Abram Hoffer Harold Foster i Andrzej Saul

Znajdź Niacyna

Immediate-release nicotinic acid (niacin)

Suplement

The speaker strongly advocates for immediate-release nicotinic acid over other forms due to its superior lipid effects and lower hepatotoxicity compared to slow-release or patent forms.

He explains that plain, quick-acting nicotinic acid is the only form that reliably improves cholesterol without liver damage, based on comparative studies. The flush is a side effect but benign. He warns against slow-release niacin and notes that inositol hexanicotinate is a patented, less effective alternative. He recommends this form for anyone seeking lipid improvement or general niacin benefits.

vs alternatywy

Compared to slow-release niacin (high hepatotoxicity), niacinamide (no lipid benefit, causes nausea at gram doses), and inositol hexanicotinate (less effective, patented, prescription-only), immediate-release nicotinic acid offers the best risk-benefit profile.

kwas nikotynowy miał te cechy pozytywne na profil lipidowy ale wykazywał efekt Flash

Powiedział też
“ani jednego w grupie 67 osób przyjmujących zwykłą szybko działającą niacynę nie stwierdzono problemową wątrobowych”— Safety data for immediate-release.
Znajdź Immediate-release

New England Journal of Medicine article January 2012

Narzędzie

The speaker references an NEJM graph showing decline in cardiovascular mortality coinciding with Linus Pauling's promotion of vitamin C and orthomolecular concepts.

He uses this reference to validate the impact of high-dose vitamin advocacy, though the article itself may not directly support all his claims. He invites listeners to view the evidence for themselves.

Zapraszam wszystkich do New England Journal of Medicine ze stycznia 2012 roku i tam jest wykres pokazujący jak zaczęły spadać choroby sercowo-naczyniowe... od czasu gdy Pan Linus pauling zaczął promować witaminy

Znajdź New

Cytaty warte uwagi

Frazy warte wyciągnięcia — kontrariańskie, konkretne lub doskonale sformułowane

6 elementów
problem stwarza to czego nie wiemy... jednak naszym prawdziwym problemem jest to co wydaje nam się że wiemy a co okazuje się nieprawdą
Encapsulates the theme of orthomolecular medicine’s suppressed knowledge.
prawda jest ukryta gdzieś głęboko dlaczego bo nie można jej opatentować
Directly states the patent-driven suppression of cheap natural remedies.
schizofrenicy są grupą ludzi która jest inteligentna widzi dużo kojarzy dużo więcej niż my to jest porównanie iPhone'a do starej Noki
Memorable, controversial analogy positioning schizophrenics as superior but vulnerable.
przeszczepienie mitochondrium z komórki nowotworowej do zdrowej wywołuje nowotwór w tej dotychczasowej komórce
Powerful mitochondrial theory of cancer causation, succinctly stated.
henkin i współpracownicy wykazali 8 przypadków zapalenia wątroby wśród 15 osób przyjmujących niacynę tą formę SR natomiast ani jednego w grupie 67 osób przyjmujących zwykłą szybko działającą niacynę
Stark data point demonstrating the danger of slow-release niacin vs immediate-release.
komórka przed śmiercią ratuje się tworząc reset a więc podział mitotyczny dochodzi do szybkiego podziału... to jest nowotwór to jest ucieczka przed śmiercią
Compelling metaphor for cancer as a desperate survival mechanism.

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Poruszone tematy

niacin-b3nicotinic-acidniacinamidecholesterolorthomolecular-medicineschizophreniamitochondrial-healthcancerflushhepatotoxicityhigh-dose-vitaminslinus-paulingabram-hofferslow-release-niacininositol-hexanicotinatenew-england-journal-of-medicine
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