High-Intensity Interval Training (Sprint Intervals) for Metabolic Reset
Sims places HIIT as one of the two pillars (alongside resistance training) to fix metabolic dysfunction. She notes that many people do moderate-intensity 'intervals' that don't produce the necessary stress. The goal is to push the body to an epigenetic shift in muscle cells that makes them less insulin-dependent, improving glucose disposal. Combined with resistance training, this retrains the hypothalamus and appetite signals. The protocol is not about burning calories during the workout but about long-term metabolic adaptation. She challenges the 'slow metabolism' excuse by asserting that the feedback mechanisms that determine metabolic rate can be rebooted through this intense stimulus.
Sprint/HIIT forces muscle glycogen depletion and rapid glucose demand, leading to upregulation of GLUT4 transporters independent of insulin (epigenetic change). It also stimulates muscle protein synthesis, increasing lean mass and basal metabolic rate. The neural stress enhances motor unit recruitment and can override the slow-twitch default in women.
high intensity work. So, if we're looking at true sprint interval training or true high intensity interval training, both of those are a very strong stress to the body, so carbohydrate, more glycogen, also building more muscle mass, and creating an epigenetic change within the muscle so that your body isn't relying as reliant on insulin as it as it usually is.

