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Menopause, Misogyny and the Medical System: Dr Sharon Malone Sets the Record Straight
~107 min
Episode Brief·YouTube

Menopause, Misogyny and the Medical System: Dr Sharon Malone Sets the Record Straight

Mary Claire Haver
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TL;DR

The four things you'd lose by not watching

4 items

TL;DR

The four things you'd lose by not watching

4 items
1

Dr. Sharon Malone reveals that the 2002 Women’s Health Initiative results were grossly misinterpreted: the real increase in breast cancer risk was less than 1 extra case per 1,000 women per year with no rise in mortality, yet a generation of women and doctors abandoned hormone therapy, costing decades of lost research and avoidable suffering.

2

Malone urges that women begin proactive ‘anticipatory guidance’ at age 40 — adjusting diet, increasing exercise, and having the hormone conversation early — to prevent the typical 10–15 pound midlife weight gain and chronic diseases, rather than trying to reverse them later.

3

At 62, Malone left her private gynecology practice with no plan and, after appearing on Michelle Obama’s podcast, became Chief Medical Officer of Alloy Health, a telemedicine platform for menopausal women, demonstrating that the post‑reproductive years can be the most productive, satisfying, and impactful.

4

Throughout the episode, she argues that women have internalized suffering as normal ‘their lot in life’ and must learn to advocate for themselves, seek second opinions when denied care, and leverage digital health to bypass a medical system slow to update its menopause knowledge.

Protocols

Concrete recipes — what, when, how much, and why

5 items

Anticipatory guidance at age 40

WhatHave an explicit conversation with women around age 40 alerting them that they will likely gain 10–15 pounds over the next decade if they maintain current habits, and advise them to pre‑emptively change diet and exercise now.
WhenAt a well‑visit around ages 38–42.
DoseOne‑time conversation with follow‑up as needed.
For whomAll women approaching perimenopause.
WhyPreventing a pound a year is far easier than losing 10 pounds ten years later.
CaveatsNone mentioned.

Malone says she used to give this ‘heads‑up’ to her patients in their late 30s and early 40s, telling them that even if they did everything right, the body changes. The advice included specifics: adjust diet, increase exercise, manage expectations. She also used that moment to discuss family history and screening (colonoscopy if parent had colon cancer, breast screening if family history, etc.) and to introduce the concept of hormone therapy so that when symptoms hit they would already be informed. She stresses that this proactive discussion calms women when later they experience brain fog or weight changes, because they know it's normal and treatable.

Mechanism

Metabolic rate slows and hormonal shifts encourage fat gain during the menopausal transition.

Personal experience

She recounts patients coming back years later and saying, ‘Dr. Malone, you told me that.’

I said, ‘You're 40. I know you're great and you're cute and everything's good. Between 40 and 50, you will gain on average 10 to 15 lb if you do exactly what you're doing right now. … So, if you want that to not happen, then I'm just telling you now these are the things you can do.’

Also said
“It's far easier to not gain a pound a year than to lose 10 lb 10 years later.”— Concisely captures the prevention logic.
“Make sure you know what your family history is so you know what things… you may be susceptible to.”— Expands the protocol to include personalized screening.

Get a second opinion for menopause treatment decisions

WhatWhen a doctor denies you hormone therapy or tells you it is dangerous, seek another physician’s opinion without guilt.
WhenAny time you encounter a clinician who refuses HT or insists you stop it based on outdated information.
DoseOne or more consultations.
For whomWomen who have done their own research and suspect their doctor is not up to date.
WhyDoctors vary widely in menopause knowledge; a second opinion may align with current evidence and your personal goals.
CaveatsOnly 1 in 5 patients advised to get a second opinion actually does so; requires self‑education first.

Malone explains that many doctors think they know everything and will not suggest a second opinion. Yet medicine is full of opinions, and a patient should not be afraid of hurting a doctor’s feelings. She tells the story of her friend who was berated by an endocrinologist for taking HT, even though her primary doctor had prescribed it. Malone also shares that she herself would sometimes recommend a second opinion when a patient wasn't comfortable with her surgical plan, because she wanted them to feel confident.

Personal experience

Her friend’s recent experience with an endocrinologist, and Malone’s own practice of suggesting second opinions for complex procedures.

If someone tells you something or someone denies you something that you think you need, I say get one… Because you know, doctors think they know everything… know what you know and know what you don't know.

Also said
“Don't be afraid and don't be certainly don't be afraid of hurting your doctor's feelings. If your doctor's offended because you get a second opinion, then they're clearly not confident in what they said.”— Directly addresses the psychological barrier many women feel.

Lifestyle fundamentals for healthy aging in menopause

WhatAdopt consistent resistance exercise, a nutrient‑dense diet, adequate sleep, alcohol reduction, no smoking, and blood pressure management.
WhenBegin by age 40 and continue lifelong.
DoseOngoing.
For whomAll women.
WhyThese behaviors directly counteract the muscle loss, bone weakening, weight gain, and cardiovascular risk that accelerate after menopause.
CaveatsRequires environmental support (safe spaces, access to healthy food) which many lack; systemic barriers must also be addressed.

Malone acknowledges this is ‘not rocket science’ but stresses that starting early is essential. She also ties this advice to the broader social determinants of health: zip code matters more than genetic code. Women need health insurance, safe neighborhoods to exercise, and grocery stores with whole foods. The conversation cannot stop at individual responsibility; it must include advocacy to remove structural barriers.

Mechanism

Resistance training preserves muscle and bone density; diet and weight management reduce metabolic strain; alcohol and tobacco accelerate aging and disease.

It's not that complicated. But, it requires some effort and it requires that you start early.

Also said
“Where you live, what your zip code is, is more determinative of your health outcomes than what your genetic code is.”— Adds the systemic dimension to the protocol.

Hormone therapy as an informed personal choice

WhatDiscuss hormone therapy with a menopause‑trained clinician; understand that HT relieves symptoms and offers bone and possibly cardiovascular protection, but stopping it will resume the underlying menopausal processes.
WhenAt symptom onset in perimenopause or early postmenopause; can be continued as long as benefits outweigh risks.
DoseIndividualized.
For whomWomen with moderate‑to‑severe symptoms or osteoporosis risk, without contraindications (e.g., personal history of breast cancer, certain clotting disorders).
WhyHT is the most effective treatment for vasomotor symptoms; it prevents osteoporosis and may reduce cardiovascular risk when started near menopause. The decision should be based on accurate risk communication, not fear.
CaveatsNot mandatory for all; the absolute breast cancer risk is very low (<1/1000/year). Stopping abruptly loses all benefits, and symptoms often return.

Malone walks through the WHI misinterpretation to explain why the fear is unwarranted, then lays out the modern understanding: HT is safe and evidence‑based for symptom management and prevention. She emphasizes that all women should have the opportunity to learn the facts and make their own decision. She is not saying everyone should take HT, but that the decision should be free of misinformation. She also warns that many clinicians outside of OB/GYN (endocrinologists, cardiologists) are still repeating the 2002 scare lines.

Mechanism

Estrogen acts on estrogen receptors throughout the body, preserving bone density, maintaining vascular function, and modulating brain neurotransmitters. The ‘timing hypothesis’ suggests that starting HT close to menopause yields cardiovascular benefit, while starting many years later does not.

Personal experience

She tells of her friend who started HT for bone density loss and was then shamed by an endocrinologist — in 2024.

I want women to have the information that they need. And you can choose to do it or not do it. And I don't want to give anyone the impression here that I think, ‘Oh my god, 100% all women need to take hormone therapy.’ All women should have the opportunity and have the information such that they can make a decision.

Also said
“Don't think that they've magically disappeared because you've been on… I think of it this way. It's like hitting the pause button… and you unpause it when you stop it.”— Prevents the common mistake of quitting HT cold turkey thinking the problem is gone.
“Even if you started later, it's still not that much excess harm, either.”— Counteracts the absolute contraindication myth for older starters.

Advocacy and self‑education before the doctor visit

WhatBefore a menopause‑related appointment, listen to credible podcasts, read books, and prepare specific questions so you can recognize when your doctor is giving outdated advice.
WhenWhenever you plan to discuss menopause concerns.
DoseOngoing self‑education.
For whomAll women navigating midlife healthcare.
WhyPatients who are informed can differentiate between evidence‑based care and ‘just an opinion’ and can insist on appropriate treatment or seek a second opinion.

Malone says that the first step is awareness, and that social media and podcasts have been a huge boon for amplifying women’s shared experiences (frozen shoulder, hair changes) that were previously dismissed as unrelated. She encourages women to approach doctors with data and questions, not to accept ‘it’s just your age’.

Speak up. But it requires you to have the good information when you walk into a doctor's office.

What's new

Personal practice updates, fresh positions, predictions

5 items

womens-health-initiative-reinterpretation

mid

Malone walks through the design flaws and statistical misreporting of the WHI, showing that the 2002 panic about hormone therapy causing breast cancer was driven by a poorly contextualized relative risk, and that the study actually found no significant harms.

Why this matters: She specifically quantifies the absolute risk (less than 1 extra breast cancer case per 1,000 women per year) and explains why the study population — older, asymptomatic women — could not answer the heart disease prevention question it was designed for.

Background

Before 2002, hormone therapy was widely prescribed for menopause symptoms and observational data suggested cardiovascular benefits. The WHI was intended to test whether HT prevented heart disease, so it intentionally enrolled women up to age 79 and excluded those with hot flashes to maintain blinding. When the trial was halted early, the press conference emphasized a 26% relative increase in breast cancer without providing absolute numbers, creating a fear that persists today.

Malone recounts how the WHI’s announcement instantly changed clinical practice: phone lines lit up, women stopped taking hormones overnight, and residency programs stopped teaching nuanced menopause care. She emphasizes that the breast cancer finding was not statistically significant and was less than one extra case per 1,000 women per year, with no increase in breast cancer mortality. Yet the fear was so pervasive that it halted not only prescribing but also ongoing international studies, and to this day no large‑scale study of postmenopausal women has been conducted by the NIH. She notes that even in 2024, specialists like endocrinologists are still telling patients to stop HT based on the same outdated fears, demonstrating how deeply the misinformation is entrenched.

Personal experience

Malone was in practice before and after the WHI and vividly describes the flood of panicked calls from patients who had been doing beautifully on hormones and quit them overnight.

That increase in the risk of breast cancer in real numbers amounted to less than one in a thousand additional cases of breast cancer. And that sounds a whole lot less scary than a 26% increase with no increase in the risk of dying from breast cancer.

Also said
“When they announced… partly it increases your risk of all these other things, cancer, uh strokes… None of which were statistically significant. And in medical world, if it's not statistically significant, it's not a finding.”— Highlights that the reported harms did not meet standard statistical thresholds for significance, yet were broadcast as definitive.
“We would have now 30 years of data. What does it look like for women who've taken hormone therapy continuously for 30 years? We would know so much more about brain health… cardiovascular disease, but water under the bridge now.”— Shows the lasting lost opportunity for research that could have answered critical longevity questions.
“It matters when you start in terms of how much benefit you're going to get. But to be honest with you, even if you started later, it's still not that much excess harm, either.”— Counters the common belief that starting HT after age 60 is inherently dangerous.

menopause-is-a-permanent-state

mid

Malone reframes menopause not as a temporary symptom window but as a lifelong biological condition; hitting ‘pause’ with hormone therapy only suspends the process, and stopping it resumes the decline.

Why this matters: Directly challenges the widespread belief that once hot flashes stop, menopause is ‘over’ — and that symptoms and risks won't return after discontinuing HT.

Background

Many women and even clinicians treat menopause as a discrete event or phase that ends. Malone points to the continued loss of bone, rise in cardiovascular risk, and metabolic changes that continue for decades.

She draws the analogy of a pause button: while on hormone therapy, symptoms and some aging processes are arrested, but once HT is stopped, the underlying biology resumes, often leading to a return of hot flashes and rapid bone loss. She stresses that women who have been on HT for years are often shocked when their symptoms return after stopping, because they believed they were ‘done’ with menopause. This misunderstanding undermines their long‑term health planning.

I always say, ‘You are never done with menopause, because menopause is never done with you.’

Also said
“I think of it this way. It's like hitting the pause button… and you unpause it when you stop it, and guess what? And that process still has to play itself out.”— Clarifies the mechanism metaphorically and explains why symptoms can re‑emerge.

career-pivot-at-62

early-to-mid

Malone left her private gynecology practice at 62 with no plan, discovered she could be happy not working, and then joined digital health startup Alloy, finding a greater sense of purpose and happiness than in her earlier career.

Why this matters: It serves as a powerful real-world model that women over 50 are not declining but entering their most intellectually productive and fulfilling phase.

Background

She had been in practice 32 years, and COVID gave her the first extended break of her adult life. After resigning, she was discovered by the Alloy founders via Michelle Obama’s podcast and became their first doctor.

Malone says she was ‘way happier at 66 than I was at 46’ because she is no longer in the overwhelm of raising children and juggling a demanding marriage with a high‑profile partner. She now controls her own schedule, has grown children, and gets to work on a mission she deeply believes in: making menopause care accessible. She urges other midlife women not to think their professional lives are over, as they have more wisdom and judgment than ever.

Personal experience

She details the exact sequence: three months off during COVID, resigning at end of 2020, and then being approached by Alloy. She describes the freedom of now being able to say ‘I’ll see you’ when her husband works late, and the joy of doing meaningful work.

I have never been more experienced. I have never had more wisdom. You need to share that with someone. And the only thing that stands in your way is not being well enough or not being physically fit enough… but it’s not because you don't have the mental capacity to do it.

Also said
“I am way happier at 66 than I was at 46. Because I was in the middle of things. I was overwhelmed at that stage. And now I can step back. I look my children are grown. I'm in control of my life.”— Personal testimony that contradicts the narrative that midlife is the beginning of decline.

medical-establishment-pushback

late

Malone describes how the medical hierarchy, including OB/GYN organizations, initially welcomed the menopause conversation but now is resisting updated messaging and guidelines, protecting the old interpretation of the WHI.

Why this matters: She brings the insider’s view that the ‘establishment’ doesn't like upstarts and that even when the same data is viewed, interpretations are entrenched, leading to a generation‑long delay in clinical change.

Background

The WHI and subsequent fear have been slowly challenged by menopause advocates. As awareness has grown, some professional societies have celebrated the attention but are now pushing back against the new, more pro‑HT narrative because it contradicts long‑held positions.

Malone says that change is always difficult and that many of the leaders are older and more entrenched. She notes that while she and Dr. Mary Claire Haver are a ‘different generation’ medically, a lot of committee members are older still and don't want to be told they were wrong. She states that the ACGME at one point claimed there wasn't enough information to include menopause in medical school curricula. She argues that if you want to have a debate about data, let's have it, but don't shut down the conversation just because it challenges authority.

I think that the medical establishment owes this generation… a debt of gratitude for elevating these conversations because this is how we're going to get more attention. This is how we're going to get legislation passed.

Also said
“There are things in medicine that are opinions. We are all sort of looking at some data, some of which is definitive, some is not, some is up for interpretation.”— Frames the disagreement as a matter of interpretation, not settled fact.

womens-acceptance-of-suffering

late

Malone identifies a cultural pattern in which women accept chronic pain, migraines, anxiety, and menopausal symptoms as normal and even praiseworthy, rather than treatable conditions.

Why this matters: It shifts the frame from ‘women don’t know’ to ‘women have been conditioned not even to complain’, making the case that the first step is recognizing suffering as optional.

She argues that women have been socialized to view suffering as part of life and are often rewarded for ‘toughing it out.’ This mentality leads to delayed diagnosis and treatment. She says there is no suffering Olympics; you don't get a medal for enduring 20 years of hot flashes. The goal should be zero unnecessary suffering, but that requires both individual advocacy and systemic change to validate women’s pain.

We have accepted suffering as our lot in life. And we suffer through a lot. We suffer through migraines and depression and anxiety and pelvic pain. And the list goes on and on… We don't even think to complain about it because we have so sort of integrated this suffering model into our existence.

Also said
“There's no suffering Olympics. You don't get a medal at the end because someone you suffered 20 years and someone else has only suffered 10. How about let's not?”— Memorable reframe that suffering is not a virtue or a competition.
Disclosed sponsorships8speaker disclosed

Alloy Health telemedicine platform

Service Sponsored · disclosed

A telehealth service designed specifically for menopausal women, connecting them with menopause‑trained doctors for evidence‑based care including hormone therapy and, recently, prescription skin care with estriol (M4 line).

DisclosureDr. Sharon Malone is Chief Medical Advisor and former Chief Medical Officer of Alloy Health. The host also runs a paid advertisement for Alloy.

Malone describes how she joined as the company’s first doctor after being discovered through the Michelle Obama podcast. She says the platform matters because women are being turned away by their own physicians and need access to clinicians who actually understand current menopause science. The host also endorses Alloy for busting the pharmacy‑line barrier and making prescription skincare accessible.

vs alternatives

Unlike general telemedicine, Alloy specifically focuses on menopause and includes clinician training in the latest evidence.

Personal experience

Malone recounts her own transition from private practice to Alloy’s Chief Medical Officer and how it gave her a new mission.

That's why Alloy and digital health because it allows us to give this information to many… It's a speed ramp, you know, for us to go through the traditional system.

Also said
“I'm the chief medical advisor at Alloy Health. But when I first started, I was their chief medical officer. So, I was their only doctor at that point.”— Authenticates her deep involvement.
Find Alloy

Grown Woman Talk: Your Guide to Getting and Staying Healthy

Book Sponsored · disclosed

Malone’s New York Times best‑selling book that is part autobiography, part prescriptive health guide, sharing stories from her own life and community to illustrate healthcare disparities and provide practical advice for women in midlife and beyond.

DisclosureWritten by guest Dr. Sharon Malone.

She explains that the book started as a ‘love letter to my sisters’ because she wanted to give health advice from a place of love, not chastisement. It addresses the mindset barriers that keep people from engaging with the medical system, drawn from her own mother’s death from colon cancer due to lack of access and fear. The book covers navigating the current, changed medical landscape.

Personal experience

She wrote it as a way to share what she wishes every woman knew, born from her own family’s experiences of loss and her decades in practice.

It was really part love letters… I wanted people to understand that I want to give you some health advice, but it comes from a place of love.

Find Grown

Midi Health telehealth clinic

Service Sponsored · disclosed

A national women’s telehealth clinic covered by major insurance, offering personalized plans for menopause including hormone therapy, nutrition, lifestyle guidance, and weight management.

DisclosureHost Dr. Mary Claire Haver runs a paid advertisement for Midi Health and states that their clinicians are professionals she trusts.

In the ad break, Haver says Midi Health is closing the gap in menopause care, providing expert evidence‑based care that treats the whole person. She highlights that it’s the only national women’s telehealth clinic covered by major insurance, making high‑quality care accessible.

Personal experience

Haver has endorsed Midi previously and states she is ‘thrilled by what Midi Health is doing.’

Midi Health is a telehealth clinic serving women in midlife with expert evidence‑based care. Their clinicians and medical leaders are professionals I trust, committed to treating the whole person.

Find Midi

Virtue Flourish hair care collection

Product Sponsored · disclosed

A hair care line formulated with Alpha Keratin 60ku for women experiencing thinning or shedding due to hormonal changes, stress, or aging.

DisclosureAd read by host offering a discount code ‘unpaused’ at jennybird.com and ‘virtue20’ at virtuelabs.com.

The ad positions Virtue’s Flourish as a restorative approach that repairs the scalp and hair from within, using bioidentical proteins recognized by the body as its own keratin.

At the heart of Flourish is Virtue's key ingredient, Alpha Keratin 60 K U clinical. This is a combination of two bioidentical proteins that are recognized by the body as its own keratin.

Find Virtue

Jenny Bird jewelry

Product Sponsored · disclosed

A jewelry brand offering bracelets, earrings, and monogram necklaces with elegant packaging and fast shipping.

DisclosureAd read; discount code ‘unpaused’ at jennybird.com.

The host shares that she has added several pieces to her own rotation and loves how they pull an outfit together effortlessly. She recommends them as thoughtful gifts for the holidays.

Personal experience

‘I’ve added a few of their pieces into my own rotation, and I love how they can pull an outfit together with zero effort.’

If you're looking for a gift that feels thoughtful and elevated, Jenny Bird is such an easy place to start.

Find Jenny

Primally Pure toxin-free body care

Product Sponsored · disclosed

A clean‑ingredient brand offering charcoal natural deodorant, almond vanilla body butter, and limited‑edition holiday bundles like vanilla mint body care.

DisclosureAd read; discount code ‘unpaused’ for 15% off at primallypure.com.

The host highlights that the deodorant is made with bioavailable ingredients that neutralize odor and minimize toxic buildup, and the body butter is moisturizing and toxin‑free.

Their charcoal natural deodorant is made with vitamin-rich, bioavailable ingredients that work with the body not only to effectively neutralize odor, but to help minimize toxic buildup.

Find Primally

Alma therapist matching platform

Service Sponsored · disclosed

A nationwide network of over 20,000 licensed therapists who accept insurance, allowing users to search and filter by gender, race, or therapeutic approach and schedule free 15‑minute consultations.

DisclosureAd read; visit helloalma.com/unpaused.

The ad emphasizes that Alma isn't about quick fixes but real human connection, and that users can save 80% on sessions through insurance.

With a nationwide network of over 20,000 diverse, licensed therapists, 99% of whom accept insurance, Alma makes finding the right care simple and affordable.

Find Alma

The New Perimenopause (pre-order)

Book Sponsored · disclosed

The host’s upcoming book on perimenopause, available for pre‑order.

DisclosureWritten by host Dr. Mary Claire Haver; mentioned at the end of the episode.

My new book, The New Perimenopause, is available for pre-order everywhere you buy books.

Find The

Notable quotes

Lines worth pulling out — contrarian, specific, or perfectly phrased

6 items
You are never done with menopause, because menopause is never done with you.
Succinctly reframes the condition as a lifelong biological state, not a temporary phase.
There's no suffering Olympics. You don't get a medal at the end because someone you suffered 20 years and someone else has only suffered 10. How about let's not?
Memorable, punchy line that challenges the cultural glorification of female stoicism.
I have never been more experienced. I have never had more wisdom. You need to share that with someone. And the only thing that stands in your way is not being well enough or not being physically fit enough… but it’s not because you don't have the mental capacity to do it.
Directly counteracts ageist narratives about midlife women’s abilities.
Where you live, what your zip code is, is more determinative of your health outcomes than what your genetic code is.
Powerful, data‑backed reminder that health disparities are structural, not personal failings.
That increase in the risk of breast cancer in real numbers amounted to less than one in a thousand additional cases of breast cancer. And that sounds a whole lot less scary than a 26% increase with no increase in the risk of dying from breast cancer.
Cuts through the most persistent fear around hormone therapy with the actual absolute risk.
We have accepted suffering as our lot in life. And we suffer through a lot. We suffer through migraines and depression and anxiety and pelvic pain. And the list goes on and on… We don't even think to complain about it because we have so sort of integrated this suffering model into our existence.
Names a widespread but rarely articulated cultural conditioning that keeps women from seeking help.

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Topics covered

menopause-carewomens-health-initiativehormone-therapyhealth-disparitiessecond-opinionmidlife-transitionsocial-media-advocacyperimenopauseanticipatory-guidanceobgyn-trainingmedical-establishmentlongevityexerciseglp1-accesssuffering-modelcareer-pivotalloy-healthgrown-woman-talkdr-sharon-malone
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