Daily protein intake of 1.2 g/kg ideal body weight
Stanfield navigates the conflicting messages about protein by presenting a nuanced synthesis. The high-protein camp emphasizes muscle mass preservation (individuals aged 70–79 losing 40% less lean mass at 1.1 vs 0.8 g/kg) and weight loss benefits (high-protein diets produce larger reductions in body weight and fat mass while preserving lean mass). The low-protein camp, led by Dr. Valter Longo, highlights a 74% increase in all-cause mortality and a fourfold rise in cancer mortality among 50–65-year-olds consuming high animal protein. Critically, the risk is not from total protein but from animal protein specifically; plant protein is associated with a 36% lower mortality risk. A 2020s meta-analysis found that the dose-response curve for lean body mass flattens after 1.3 g/kg, meaning 1.6 g/kg provides diminishing returns for most people. Stanfield therefore settles on 1.2 g/kg as a pragmatic target that maximizes benefits while minimizing risks, with strict guidance on protein source.
Dietary protein provides essential amino acids that stimulate muscle protein synthesis via mTOR signalling, helping counteract age-related sarcopenia. Higher protein also increases satiety and diet-induced thermogenesis, aiding weight management. The cancer link primarily involves specific animal-derived amino acids and possibly growth factor pathways (e.g., IGF-1), which are less stimulated by plant proteins and fish protein due to differing amino acid profiles and associated bioactive compounds.
Stanfield says: 'Personally, I aim for 1.2 g of protein intake per kilogram of ideal body weight per day. That's what I personally take and that's what I recommend to my patients.'
We can increase protein intake above that 0.8 g per kilogram of ideal body weight per day target to get the gains that we see from higher protein diets without increasing the risks to our health.

