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Episode
Simon Hill on The Truth About Seed Oils & What’s Actually Making Us Sick
~100 min
Episode Brief·YouTube

Simon Hill on The Truth About Seed Oils & What’s Actually Making Us Sick

Mark Hyman
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TL;DR

The four things you'd lose by not watching

4 items

TL;DR

The four things you'd lose by not watching

4 items
1

Seed oils are not the primary driver of chronic disease; the dramatic rise of hyper-palatable ultra-processed foods (UPFs) is the main explanation, while biomarker data show higher linoleic acid levels are associated with lower mortality and cardiovascular risk.

2

Adequate total protein intake (1.2–1.6 g/kg/day) combined with regular resistance training is the cornerstone for muscle maintenance; plant protein performs equally to animal protein when intake is optimized, contrary to older assumptions.

3

Simon Hill shared his own N-of-1 experiment: swapping extra‑virgin olive oil for coconut oil raised his LDL‑cholesterol and ApoB by 30%, demonstrating the importance of personalized fat choices and blood testing.

4

The core dietary advice is a Mediterranean‑style whole‑food pattern with extra‑virgin olive oil, fatty fish or EPA/DHA supplements, nuts, seeds, and legumes, while avoiding ultra‑processed foods regardless of their fat type.

Recommendations

Products, supplements, and tools mentioned in the episode

1 item

Extra‑virgin olive oil

Product

Simon cooks with extra‑virgin olive oil as his primary culinary fat and sees it as a cornerstone of the Mediterranean pattern, offering a rich source of monounsaturated fats and polyphenols.

Throughout the conversation, Simon positioned extra‑virgin olive oil as the default oil for home cooking, contrasting it with both industrial seed oils in ultra‑processed foods and with coconut oil, which he personally avoids due to its saturated fat content raising his LDL. He emphasised that the fat matrix matters: extra‑virgin olive oil contains oleic acid and antioxidant polyphenols that are associated with improved endothelial function and reduced oxidation of LDL particles. His advice is to use it liberally on vegetables and in dressings, avoiding high‑heat frying that degrades the delicate compounds. This recommendation fits within the broader Mediterranean dietary pattern that he advocates.

vs alternatives

Compared to other vegetable oils often criticised for extraction methods, extra‑virgin olive oil is minimally processed (cold‑pressed) and retains beneficial phytochemicals; compared to coconut oil, it lowers cardiovascular risk markers in most individuals.

Personal experience

Simon stated, “olive oil is the oil that I cook with, extra‑virgin olive oil.” He observed that removing it and substituting coconut oil led to a 30% rise in his LDL and ApoB, so he has returned to olive oil as his staple.

Olive oil is the oil that I cook with, extra‑virgin olive oil.

Also said
“The swap that I made was olive oil … I was swapping that out and adding in coconut oil … and that saw a reduction in monounsaturated fats and an increase in saturated fats.”— Shows the deliberate choice to use olive oil and the negative effect of replacing it.
Find Extra‑virgin

Notable quotes

Lines worth pulling out — contrarian, specific, or perfectly phrased

2 items
When I look at the increase in chronic disease over the last 50 or 70 years to me the most obvious explanation for that is not an increase in the consumption of vegetable oils or seed oils. It’s an increase in the consumption of hyper palatable ultra‑processed foods.
Directly reframes the seed oil debate and places blame on the overall food matrix, a succinct summary of his evidence‑based position.
I find that the linoleic acid seed oil consumption data again coming back to red blood cell content and also adipose tissue they have people with higher linoleic acid in their tissue have lower risk of heart disease cancer mortality and total mortality.
Puts a hard biomarker endpoint behind the defence of seed oils, making the epidemiological argument concrete.

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Topics covered

seed-oilsultra-processed-foodslinoleic-acidomega-6omega-3saturated-fatlow-fat-diet-historymediterranean-dietprotein-intakeplant-protein-vs-animal-proteinmuscle-masssarcopeniaresistance-trainingpower-traininganabolic-resistancepersonalised-nutritionblood-testingapobn-of-1-experimentfood-environment
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Educational summary of the cited expert source — not medical advice. Open the source recording linked above and consult a qualified physician before acting on any protocol.