You've Been LIED TO About Seed Oils! | Educational Video | Biolayne

Layne Norton

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A recent study found that consuming soybean oil (high in linoleic acid) did not increase inflammatory markers or oxidized LDL compared to palm oil (high in saturated fat), challenging common anti-seed oil claims.

LDL oxidation primarily occurs within the endothelium, not in the blood plasma, and is driven by LDL concentration, which is increased by saturated fats.

Substituting seed oils for saturated fats generally has neutral or positive effects on inflammation, cardiovascular disease, insulin sensitivity, and liver fat.

The claim that linoleic acid in seed oils is inflammatory due to conversion to arachidonic acid and prostaglandins is not supported by evidence showing no increase in these markers.

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Seed oils and inflammation

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Contrary to popular belief, seed oils do not increase inflammatory markers in the body.

Why this matters: This directly refutes a widely held belief among anti-seed oil proponents that linoleic acid in seed oils causes inflammation.

Background

The anti-seed oil movement often claims that linoleic acid, found in seed oils, is inflammatory because it can be converted to arachidonic acid, which then forms inflammatory prostaglandins.

Layne Norton discusses a new study comparing the consumption of soybean oil (high in linoleic acid) with palm oil (high in saturated fat). The study found no difference in various inflammatory markers between the two groups, directly contradicting the idea that seed oils are inflammatory. He emphasizes that despite the theoretical pathway for linoleic acid to become inflammatory compounds, actual human studies do not show an increase in these markers or overall inflammation.

New study just came out looking at either consuming soybean oil at like 30 grams per day versus 30 grams of palm oil, which palm oil is high in saturated fat. Soybean oil is high in linoleic acid, which amongst the anti-seed oil people, it's like linoleic acid is the devil because it increases inflammation because linoleic acid can be converted to arachidonic acid and arachidonic acid can be turned into prostaglandins which are inflammatory. Therefore, seed oils inflammatory. kill you. Except they don't because when you actually give high amounts of seaw walls, they don't increase inflammatory markers and they don't increase arachidonic acid.

Also said

“So this has been shown in in multiple studies now. So in that study, they looked at various inflammatory markers and they basically saw no difference.”— Highlights that the finding is not isolated to a single study but supported by multiple research efforts.

Seed oils and oxidized LDL

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Seed oils do not increase oxidized LDL levels, a claim often made by critics.

Why this matters: This challenges another common argument against seed oils, specifically regarding their impact on cardiovascular health.

Background

Critics like Paul Saladino often suggest that seed oils increase oxidized LDL, which is linked to heart disease.

Layne Norton references the same study, noting that it also found no difference in oxidized LDL levels between the soybean oil group (high in polyunsaturated fats) and the palm oil group (high in saturated fat). He explains that LDL oxidation primarily occurs within the endothelium, not in the blood plasma, due to the presence of antioxidants in plasma. The key driver for LDL penetrating the endothelium and subsequently oxidizing is the concentration of LDL, which is elevated by diets high in saturated fat, not polyunsaturated fats.

They also saw no difference in oxidized LDL, which is another one that our friend Paul Sino likes to point out. Well, you don't want to eat seahorses because it's going to increase oxidative LDL. Nope. This study they had people eating way more linoleic acid in the soybean group, way more polyunsaturated fats versus the saturated fat group, and there was no difference in oxidized LDL.

Also said

“You have to understand where LDL gets oxidized. It doesn't really get oxidized in the blood in the plasma because there's a lot of antioxidants present. LDL gets oxidized in the endothelium.”— Explains the specific location and conditions under which LDL oxidation occurs, debunking the simple 'polyunsaturated fats oxidize easily' argument.

“Diets that are high in saturated fat increase LDL concentrations in the blood and the penetration of the endothelium by the LDL is concentration driven.”— Identifies saturated fat as the primary dietary factor influencing LDL concentration and subsequent endothelial penetration, linking it to the root cause of oxidation.

Saturated fat vs. seed oils for health outcomes

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Saturated fat is a greater concern for heart disease and inflammation than seed oils.

Why this matters: This is a direct reversal of the common anti-seed oil narrative, positioning saturated fat as the more problematic dietary component.

Layne Norton concludes that if one is concerned about heart disease and inflammation, saturated fat should be the primary worry. He states that when seed oils are substituted for saturated fats in the diet, the effects on inflammation, cardiovascular disease, insulin sensitivity, and liver fat are either neutral or positive. This reinforces his earlier points that seed oils are neither inflammatory nor contributors to oxidized LDL, and in fact, replacing saturated fats with them can be beneficial.

And if you're worried about heart disease and inflammation, you should be way more worried about saturated fat. Because when it comes to inflammation, cardiovascular disease, insulin sensitivity, liver fat, when you substitute seed oils in place of saturated fat, they're either neutral or positive effects. Worst case is neutral.

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Except they don't because when you actually give high amounts of seaw walls, they don't increase inflammatory markers and they don't increase arachidonic acid.

Directly refutes the core mechanism claimed by anti-seed oil advocates regarding inflammation.

You have to understand where LDL gets oxidized. It doesn't really get oxidized in the blood in the plasma because there's a lot of antioxidants present. LDL gets oxidized in the endothelium.

Provides a crucial mechanistic detail that explains why the 'polyunsaturated fats oxidize easily' argument is flawed in the context of human physiology.

Diets that are high in saturated fat increase LDL concentrations in the blood and the penetration of the endothelium by the LDL is concentration driven.

Highlights the primary driver of LDL oxidation and links it directly to saturated fat intake, shifting the focus from seed oils.

We care about data more than your feelings.

A strong, declarative statement emphasizing a scientific, evidence-based approach over popular opinion or emotional responses to dietary advice.

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Topics covered

seed oilsinflammationlinoleic acidarachidonic acidprostaglandinssoybean oilpalm oilsaturated fatoxidized ldlpaul saladinoendotheliumantioxidantscardiovascular diseaseinsulin sensitivityliver fat